Distinct cytotoxic mechanisms of pristine versus hydroxylated fullerene
…, M Mirkovic, M Dramicanin, L Harhaji… - Toxicological …, 2006 - academic.oup.com
The mechanisms underlying the cytotoxic action of pure fullerene suspension (nano-C 60 )
and water-soluble polyhydroxylated fullerene [C 60 (OH) n ] were investigated. Crystal violet …
and water-soluble polyhydroxylated fullerene [C 60 (OH) n ] were investigated. Crystal violet …
Dual antiglioma action of metformin: cell cycle arrest and mitochondria-dependent apoptosis
A Isakovic, L Harhaji, D Stevanovic, Z Markovic… - Cellular and molecular …, 2007 - Springer
The present study reports for the first time a dual antiglioma effect of the well-known antidiabetic
drug metformin. In low-density cultures of the C6 rat glioma cell line, metformin blocked …
drug metformin. In low-density cultures of the C6 rat glioma cell line, metformin blocked …
The mechanism of cell-damaging reactive oxygen generation by colloidal fullerenes
…, L Vucicevic, K Janjetovic, A Isakovic, L Harhaji… - Biomaterials, 2007 - Elsevier
… ethanol at a concentration of 25 or 11 mg/l, respectively. After the mixture was purged with …
60 or EtOH/C 60 filtrate at a rate of 2 l/min, while being continuously stirred. The more volatile …
60 or EtOH/C 60 filtrate at a rate of 2 l/min, while being continuously stirred. The more volatile …
Multiple mechanisms underlying the anticancer action of nanocrystalline fullerene
L Harhaji, A Isakovic, N Raicevic, Z Markovic… - European journal of …, 2007 - Elsevier
Using the rat glioma cell line C6 and the human glioma cell line U251, we demonstrate the
multiple mechanisms underlying the in vitro anticancer effects of the C 60 fullerene water …
multiple mechanisms underlying the in vitro anticancer effects of the C 60 fullerene water …
Anti-tumor effect of Coriolus versicolor methanol extract against mouse B16 melanoma cells: in vitro and in vivo study
LJ Harhaji, S Mijatović, D Maksimović-Ivanić… - Food and chemical …, 2008 - Elsevier
Numerous studies have shown immunostimulatory and anti-tumor effects of water and
standardized aqueous ethanol extracts derived from the medicinal mushroom, Coriolus versicolor, …
standardized aqueous ethanol extracts derived from the medicinal mushroom, Coriolus versicolor, …
Anti-glioma action of aloe emodin: the role of ERK inhibition
…, J Radovic, DJ Miljkovic, LJ Harhaji… - Cellular and molecular …, 2005 - Springer
The effect of aloe emodin (AE), a herbal anthraquinone derivative, on the rat C6 glioma cell
line was investigated. In addition to cell cycle block and caspasedependent apoptosis, AE …
line was investigated. In addition to cell cycle block and caspasedependent apoptosis, AE …
Macrophage migration inhibitory factor (MIF) is necessary for progression of autoimmune diabetes mellitus
…, M Momcilovic, D Popadic, L Harhaji… - Journal of Cellular …, 2008 - Wiley Online Library
… as diabetics when two consecutive days of glycosuria were followed by glycemia above 11.8
mmol/l. … Animals with glycemia above 10 mmol/l for two consecutive measurements were …
mmol/l. … Animals with glycemia above 10 mmol/l for two consecutive measurements were …
Astrocyte‐induced regulatory T cells mitigate CNS autoimmunity
…, V Bumbasirevic, A Backovic, I Cvetkovic, L Harhaji… - Glia, 2004 - Wiley Online Library
Although astrocytes presumably participate in maintaining the immune privilege of the central
nervous system (CNS), the mechanisms behind their immunoregulatory properties are still …
nervous system (CNS), the mechanisms behind their immunoregulatory properties are still …
Induction of experimental autoimmune encephalomyelitis in Dark Agouti rats without adjuvant
…, Z Ramic, V Bumbasirevic, L Harhaji… - Clinical & …, 2004 - academic.oup.com
Experimental autoimmune encephalomyelitis (EAE) is a well-recognized model for multiple
sclerosis (MS) in humans. However, adjuvants used with encephalitogens to induce EAE …
sclerosis (MS) in humans. However, adjuvants used with encephalitogens to induce EAE …
Anticancer properties of the novel nitric oxide-donating compound (S,R)-3-phenyl-4,5-dihydro-5-isoxazole acetic acid-nitric oxide in vitro and in vivo
D Maksimovic-Ivanic, S Mijatovic, L Harhaji… - Molecular cancer …, 2008 - AACR
… Sodium nitrite (6.9 g, 100 mmol/L) was added in portions to a stirred solution of tetronic
acid (10 g, 100 mmol/L) in 3 mol/L HCl (60 mL). The purple solution was stirred for 15 min at …
acid (10 g, 100 mmol/L) in 3 mol/L HCl (60 mL). The purple solution was stirred for 15 min at …