Metabolic profiles of placenta in preeclampsia using HR-MAS MRS metabolomics

M Austdal, LCV Thomsen, LH Tangerås, B Skei… - Placenta, 2015 - Elsevier
Introduction Preeclampsia is a heterogeneous gestational disease characterized by maternal
hypertension and proteinuria, affecting 2–7% of pregnancies. The disorder is initiated by …

[HTML][HTML] First trimester urine and serum metabolomics for prediction of preeclampsia and gestational hypertension: a prospective screening study

M Austdal, LH Tangerås, RB Skråstad… - International journal of …, 2015 - mdpi.com
Hypertensive disorders of pregnancy, including preeclampsia, are major contributors to
maternal morbidity. The goal of this study was to evaluate the potential of metabolomics to …

[CITATION][C] Neurodevelopmental effects of bisphenol A and phthalates studied in in ovo exposed chicken to model prenatal exposure

KE Rakkestad, G Mathisen, LP Austdal, RE Paulsen - Toxicology Letters, 2014 - infona.pl
… Kirsten Eline Rakkestad, Gro Mathisen, Lars Peter Austdal, Ragnhild Elisabeth Paulsen …

[HTML][HTML] Antiepileptic drugs lamotrigine and valproate differentially affect neuronal maturation in the developing chick embryo, yet with PAX6 as a potential common …

D Zosen, LPE Austdal, S Bjørnstad, JS Lumor… - Neurotoxicology and …, 2022 - Elsevier
Exposing the immature nervous system to specific antiepileptic drugs (AEDs) during
pregnancy is linked to neurodevelopmental disorders such as autism spectrum disorder (ASD). …

Biomarkers for prediction and characterization of preeclampsia using magnetic resonance metabolomics

M Austdal - 2015 - ntnuopen.ntnu.no
Hypertensive diseases of pregnancy are major contributors to maternal and fetal morbidity
worldwide. Preeclampsia, characterized by gestational hypertension and proteinuria …

[HTML][HTML] Peripherally administered persistent organic pollutants distribute to the brain of developing chicken embryo in concentrations relevant for human exposure

A Yadav, S Verhaegen, MG Hadera, HF Berntsen… - NeuroToxicology, 2022 - Elsevier
Persistent organic pollutants (POPs) can reach the fetal brain and contribute to developmental
neurotoxicity. To explore the distribution of POPs to the fetal brain, we exposed chicken …

[HTML][HTML] Exposure to a human relevant mixture of persistent organic pollutants or to perfluorooctane sulfonic acid alone dysregulates the developing cerebellum of …

A Yadav, S Verhaegen, P Filis, D Domanska… - Environment …, 2022 - Elsevier
Prenatal exposure to persistent organic pollutants (POPs) is associated with neurodevelopmental
disorders. In the present study, we explored whether a human-relevant POP mixture …

Application of metabolomics to preeclampsia diagnosis

BF Nobakht M. Gh - Systems biology in reproductive medicine, 2018 - Taylor & Francis
Preeclampsia is a multifactorial disorder defined by hypertension and increased urinary
protein excretion during pregnancy. It is a significant cause of maternal and neonatal deaths …

How to prevent chick culling in the poultry industry? Discovery of a new biomarker for in ovo gender screening

N Drouin, HL Elfrink, W Bruins, S Koval, AC Harms… - bioRxiv, 2023 - biorxiv.org
Chicken eggs are one of the most consumed foods worldwide. However, the practice of chicken
culling in the poultry industry involves unnecessary animal suffering and finding a way to …

[HTML][HTML] Cerebellum and prematurity: a complex interplay between disruptive and dysmaturational events

G Spoto, G Amore, L Vetri, G Quatrosi… - Frontiers in Systems …, 2021 - frontiersin.org
The cerebellum plays a critical regulatory role in motor coordination, cognition, behavior,
language, memory, and learning, hence overseeing a multiplicity of functions. Cerebellar …