Neuronal release of soluble nucleotidases and their role in neurotransmitter inactivation
LD Todorov, S Mihaylova-Todorova, TD Westfall… - Nature, 1997 - nature.com
letters to nature Page 1 letters to nature centred on the TV screen during the course of
studying each cell. We defined the size of each cell's receptive field centre by independently …
studying each cell. We defined the size of each cell's receptive field centre by independently …
ATP as a cotransmitter in sympathetic nerves and its inactivation by releasable enzymes
DP Westfall, LD Todorov… - Journal of Pharmacology …, 2002 - ASPET
… There is also evidence that sympathetic nerves in blood vessels release nucleotidases (eg,
rat caudal and rabbit saphenous artery; LD Todorov and ST Mihaylova-Todorova, …
rat caudal and rabbit saphenous artery; LD Todorov and ST Mihaylova-Todorova, …
Evidence for the differential release of the cotransmitters ATP and noradrenaline from sympathetic nerves of the guinea‐pig vas deferens.
LD Todorov, S Mihaylova-Todorova… - The Journal of …, 1996 - Wiley Online Library
1. Experiments were carried out to quantify the stimulation‐evoked overflow of catecholamines
and purines (ATP, ADP, AMP and adenosine) from an in vitro sympathetic nerve‐smooth …
and purines (ATP, ADP, AMP and adenosine) from an in vitro sympathetic nerve‐smooth …
Modulation of purinergic neurotransmission
P Sneddon, TD Westfall, LD Todorov… - Progress in brain …, 1999 - Elsevier
Publisher Summary This chapter highlights some recent developments in the understanding
of ATP as a cotransmitter. Four main topics of purinergic research are emphasized in the …
of ATP as a cotransmitter. Four main topics of purinergic research are emphasized in the …
Differential cotransmission in sympathetic nerves: role of frequency of stimulation and prejunctional autoreceptors
LD Todorov, ST Mihaylova-Todorova, RA Bjur… - … of Pharmacology and …, 1999 - ASPET
Recent reports have suggested that sympathetic nerves may store separately and release
independently the cotransmitters ATP and norepinephrine (NE). It is conceivable therefore …
independently the cotransmitters ATP and norepinephrine (NE). It is conceivable therefore …
Enzyme kinetics and pharmacological characterization of nucleotidases released from the guinea pig isolated vas deferens during nerve stimulation: evidence for a …
ST Mihaylova-Todorova, LD Todorov… - Journal of Pharmacology …, 2002 - ASPET
Previously, we have demonstrated that stimulation of the sympathetic nerves of the guinea
pig vas deferens evokes release not only of the cotransmitters ATP and norepinephrine but …
pig vas deferens evokes release not only of the cotransmitters ATP and norepinephrine but …
The effect of P2 receptor antagonists and ATPase inhibition on sympathetic purinergic neurotransmission in the guinea‐pig isolated vas deferens
P Sneddon, TD Westfall, LD Todorov… - British journal of …, 2000 - Wiley Online Library
Intracellular microelectrodes were used to record the transmembrane potential and excitatory
junction potentials (ejps) produced by sympathetic nerve stimulation (1 Hz) in smooth …
junction potentials (ejps) produced by sympathetic nerve stimulation (1 Hz) in smooth …
Inhibitory and facilitatory effects of purines on transmitter release from sympathetic nerves.
LD Todorov, RA Bjur, DP Westfall - Journal of Pharmacology and …, 1994 - ASPET
The effects of several purinoceptor agonists and antagonists on norepinephrine overflow
were examined in the electrically field stimulated vas deferens and saphenous artery of the …
were examined in the electrically field stimulated vas deferens and saphenous artery of the …
Release of soluble nucleotidases: a novel mechanism for neurotransmitter inactivation?
C Kennedy, LD Todorov, S Mihaylova-Todorova… - Trends in …, 1997 - cell.com
(1) When the vas deferens was superfused for 1min with a solution containing exogenous ε-ATP
(100 nM), almost no degradation was detected (Fig. 3a). However, if the sympathetic …
(100 nM), almost no degradation was detected (Fig. 3a). However, if the sympathetic …
Correlation between the release of the sympathetic neurotransmitter ATP and soluble nucleotidases from the guinea pig vas deferens
S Mihaylova-Todorova, LD Todorov… - Journal of Pharmacology …, 2001 - ASPET
Recently, we have shown that by releasing specific nucleotidases the sympathetic nerves of
the guinea pig vas deferens may regulate the metabolism of extracellular adenine …
the guinea pig vas deferens may regulate the metabolism of extracellular adenine …