User profiles for K. S. Clark
Kenneth L ClarkUSDA Forest Service Verified email at usda.gov Cited by 7229 |
[HTML][HTML] Monitoring tumorigenesis and senescence in vivo with a p16INK4a-luciferase model
CE Burd, JA Sorrentino, KS Clark, DB Darr… - Cell, 2013 - cell.com
Monitoring cancer and aging in vivo remains experimentally challenging. Here, we describe
a luciferase knockin mouse (p16 LUC ), which faithfully reports expression of p16 INK4a , a …
a luciferase knockin mouse (p16 LUC ), which faithfully reports expression of p16 INK4a , a …
Mutation-specific RAS oncogenicity explains NRAS codon 61 selection in melanoma
…, W Liu, MV Huynh, MA Waqas, JE Gillahan, KS Clark… - Cancer discovery, 2014 - AACR
NRAS mutation at codons 12, 13, or 61 is associated with transformation; yet, in melanoma,
such alterations are nearly exclusive to codon 61. Here, we compared the melanoma …
such alterations are nearly exclusive to codon 61. Here, we compared the melanoma …
An oncogenic Ezh2 mutation induces tumors through global redistribution of histone 3 lysine 27 trimethylation
…, JM Simon, JY Liu, J Paulk, J Xiong, KS Clark… - Nature medicine, 2016 - nature.com
B cell lymphoma and melanoma harbor recurrent mutations in the gene encoding the EZH2
histone methyltransferase (EZH2), but the carcinogenic role of these mutations is unclear. …
histone methyltransferase (EZH2), but the carcinogenic role of these mutations is unclear. …
Canonical and non-canonical NF-κB signaling promotes breast cancer tumor-initiating cells
MF Kendellen, JW Bradford, CL Lawrence, KS Clark… - Oncogene, 2014 - nature.com
Tumor-initiating cells (TICs) are a sub-population of cells that exhibit a robust ability to self-renew
and contribute to the formation of primary tumors, the relapse of previously treated …
and contribute to the formation of primary tumors, the relapse of previously treated …
Interpreting species‐specific variation in tree‐ring oxygen isotope ratios among three temperate forest trees
… The CO 2 exchange between the forest and the atmosphere (NEE) was measured by the
eddy-covariance technique as detailed in Clark et al. (2010). Gross primary productivity (GPP) …
eddy-covariance technique as detailed in Clark et al. (2010). Gross primary productivity (GPP) …
Caffeine enhances activity thermogenesis and energy expenditure in rats
KS Clark, C Coleman, R Shelton… - Clinical and …, 2019 - Wiley Online Library
Caffeine and its derivatives have been used, alone and in combination with other phytochemicals,
as weight‐loss supplements. Caffeine affects several physiological and behavioural …
as weight‐loss supplements. Caffeine affects several physiological and behavioural …
[HTML][HTML] Cloning and functional expression of a voltage-gated calcium channel α1 subunit from jellyfish
MC Jeziorski, RM Greenberg, KS Clark… - Journal of Biological …, 1998 - ASBMB
Voltage-gated Ca 2+ channels in vertebrates comprise at least seven molecular subtypes,
each of which produces a current with distinct kinetics and pharmacology. Although several …
each of which produces a current with distinct kinetics and pharmacology. Although several …
Population responses to a historic drought across the range of the common monkeyflower (Mimulus guttatus)
…, KA Morioka, JM Colicchio, KS Clark… - American Journal of …, 2021 - Wiley Online Library
PREMISE Due to climate change, more frequent and intense periodic droughts are predicted
to increasingly pose major challenges to the persistence of plant populations. When a …
to increasingly pose major challenges to the persistence of plant populations. When a …
What determines the activity of antimicrobial and cytolytic peptides in model membranes
KS Clark, J Svetlovics, AN McKeown, L Huskins… - Biochemistry, 2011 - ACS Publications
We previously proposed three hypotheses relating the mechanism of antimicrobial and
cytolytic peptides in model membranes to the Gibbs free energies of binding and insertion into …
cytolytic peptides in model membranes to the Gibbs free energies of binding and insertion into …
An investigation of the uroselective properties of four novel α1a-adrenergic receptor subtype-selective antagonists
VL Pulito, X Li, SS Varga, LS Mulcahy, KS Clark… - … of Pharmacology and …, 2000 - ASPET
The development of α 1a -adrenergic receptor (AR) subtype-selective antagonists is likely to
result in uroselective agents that effectively treat benign prostatic hyperplasia (BPH) …
result in uroselective agents that effectively treat benign prostatic hyperplasia (BPH) …