Demyelination: the role of reactive oxygen and nitrogen species
KJ Smith, R Kapoor, PA Felts - Brain pathology, 1999 - Wiley Online Library
This review summarises the role that reactive oxygen and nitrogen species play in demyelination,
such as that occurring in the inflammatory demyelinating disorders multiple sclerosis …
such as that occurring in the inflammatory demyelinating disorders multiple sclerosis …
The role of nitric oxide in multiple sclerosis
KJ Smith, H Lassmann - The Lancet Neurology, 2002 - thelancet.com
Nitric oxide (NO) is a free radical found at higher than normal concentrations within inflammatory
multiple sclerosis (MS) lesions. These high concentrations are due to the appearance …
multiple sclerosis (MS) lesions. These high concentrations are due to the appearance …
Utility of transcranial Doppler ultrasound for the integrative assessment of cerebrovascular function
There is considerable utility in the use of transcranial Doppler ultrasound (TCD) to assess
cerebrovascular function. The brain is unique in its high energy and oxygen demand but …
cerebrovascular function. The brain is unique in its high energy and oxygen demand but …
Identification of FAP locus genes from chromosome 5q21
…, LK Su, B Vogelstein, TM Bryan, DB Levy, KJ Smith… - Science, 1991 - science.org
Recent studies suggest that one or more genes on chromosome 5q21 are important for the
development of colorectal cancers, particularly those associated with familial adenomatous …
development of colorectal cancers, particularly those associated with familial adenomatous …
Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients
…, DB Levy, TM Bryan, AC Preisinger, KJ Smith… - Science, 1991 - science.org
Previous studies suggested that one or more genes on chromosome 5q21 are responsible
for the inheritance of familial adenomatous polyposis (FAP) and Gardner's syndrome (GS), …
for the inheritance of familial adenomatous polyposis (FAP) and Gardner's syndrome (GS), …
Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers
…, B Vogelstein, TM Bryan, DB Levy, KJ Smith… - Science, 1991 - science.org
Recent studies have suggested the existence of a tumor suppressor gene located at
chromosome region 5q21. DNA probes from this region were used to study a panel of sporadic …
chromosome region 5q21. DNA probes from this region were used to study a panel of sporadic …
Molecular determinants of dysplasia in colorectal lesions
J Jen, SM Powell, N Papadopoulos, KJ Smith… - Cancer research, 1994 - AACR
One hallmark of malignant potential is dysplasia, the disruption of normal morphology.
While it is generally recognized that cancer is the result of a series of genetic changes, the …
While it is generally recognized that cancer is the result of a series of genetic changes, the …
Regional brain blood flow in man during acute changes in arterial blood gases
Key points • The partial pressures of arterial carbon dioxide ( ) and oxygen ( ) has a marked
influence on brain blood flow. • It is unclear if the larger brain arteries are also sensitive to …
influence on brain blood flow. • It is unclear if the larger brain arteries are also sensitive to …
Pathogenesis of Guillain–Barré syndrome
…, RDM Hadden, NA Gregson, KJ Smith - Journal of …, 1999 - Elsevier
Recent neurophysiological and pathological studies have led to a reclassification of the
diseases that underlie Guillain-Barré syndrome (GBS) into acute inflammatory demyelinating …
diseases that underlie Guillain-Barré syndrome (GBS) into acute inflammatory demyelinating …
Association of diabetes with anxiety: a systematic review and meta-analysis
OBJECTIVES: Anxiety has been shown to be associated with poor outcomes in people with
diabetes. However, there has been little research which has specifically examined whether …
diabetes. However, there has been little research which has specifically examined whether …