Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody

DR Burton, J Pyati, R Koduri, SJ Sharp, GB Thornton… - Science, 1994 - science.org
The ability of antibodies to neutralize diverse primary isolates of human immunodeficiency
virus-type 1 in vitro has been questioned, with implications for the likely efficacy of vaccines. A …

Cloning and functional expression of the human histamine H3 receptor

…, BL Roland, SJ Wilson, X Jiang, J Pyati… - Molecular …, 1999 - ASPET
Histamine regulates neurotransmitter release in the central and peripheral nervous systems
through H 3 presynaptic receptors. The existence of the histamine H 3 receptor was …

Cloning and pharmacological characterization of a fourth histamine receptor (H4) expressed in bone marrow

…, X Jiang, SJ Wilson, CL Hofstra, J Blevitt, J Pyati… - Molecular …, 2001 - ASPET
Histamine is a multifunctional hormone that regulates smooth muscle contraction in the
airways, acid secretion in the gut, and neurotransmitter release in the central nervous system …

Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not …

…, QJ Sattentau, J Pyati, R Koduri, J Robinson… - Journal of …, 1995 - Am Soc Microbiol
A panel of anti-gp120 human monoclonal antibodies (HuMAbs), CD4-IgG, and sera from
people infected with human immunodeficiency virus type 1 (HIV-1) was tested for neutralization …

[HTML][HTML] The pharmacological and functional characteristics of the serotonin 5-HT3A receptor are specifically modified by a 5-HT3B receptor subunit

AE Dubin, R Huvar, MR D'Andrea, J Pyati… - Journal of Biological …, 1999 - ASBMB
While homomers containing 5-HT 3A subunits form functional ligand-gated serotonin (5-HT)
receptors in heterologous expression systems (Jackson, MB, and Yakel, JL (1995) Annu. …

Anatomical distribution of prolactin-releasing peptide and its receptor suggests additional functions in the central nervous system and periphery

BL Roland, SW Sutton, SJ Wilson, L Luo, J Pyati… - …, 1999 - academic.oup.com
A recently identified neuropeptide with PRL-releasing capabilities binds to and activates a
previously known orphan G protein-coupled receptor, GPR10. We initiated a study to define …

Cloning of rat histamine H3 receptor reveals distinct species pharmacological profiles

TW Lovenberg, J Pyati, H Chang, SJ Wilson… - … of Pharmacology and …, 2000 - ASPET
The recent cloning and characterization of the human histamine H 3 receptor cDNA marked
a significant step toward a greater understanding of the role of this receptor in the central …

Human combinatorial antibody libraries to hepatitis B surface antigen.

…, R Graff, J DeGraw, J Pyati… - Proceedings of the …, 1992 - National Acad Sciences
… The FR4 region of the light-chain J domain has also contributed to the diversity of these
clones. The nucleotide sequence results for the JM clones examined predict four distinct light-…

Cloning differentially expressed mRNAs

…, GMC Poirier, PC Wagaman, J Chambers, J Pyati… - Nature …, 1996 - nature.com
Differential gene expression occurs in the process of development, maintenance, injury,
and death of unicellular as well as complex organisms. Differentially expressed genes are …

Zebrafish as a powerful vertebrate model system for in vivo studies of cell death

UJ Pyati, AT Look, M Hammerschmidt - Seminars in cancer biology, 2007 - Elsevier
Understanding and manipulating cell death pathways are critical to our ability to treat human
degenerative diseases and cancer. The zebrafish Danio rerio, a common aquatic pet, has …