User profiles for J. Fichna
Jakub FichnaMedical University of Lodz, Poland Verified email at umed.lodz.pl Cited by 10407 |
[HTML][HTML] The role of microbiota-gut-brain axis in neuropsychiatric and neurological disorders
…, A Zielińska, E Poleszak, J Fichna… - Pharmacological …, 2021 - Elsevier
Emerging evidence indicates that the gut microbiota play a crucial role in the bidirectional
communication between the gut and the brain suggesting that the gut microbes may shape …
communication between the gut and the brain suggesting that the gut microbes may shape …
The endomorphin system and its evolving neurophysiological role
J Fichna, A Janecka, J Costentin, JC Do Rego - Pharmacological reviews, 2007 - ASPET
Endomorphin-1 (Tyr-Pro-Trp-Phe-NH 2 ) and endomorphin-2 (Tyr-Pro-Phe-Phe-NH 2 ) are
two endogenous opioid peptides with high affinity and remarkable selectivity for the μ-opioid …
two endogenous opioid peptides with high affinity and remarkable selectivity for the μ-opioid …
[HTML][HTML] The role of oxidative stress in pathogenesis and treatment of inflammatory bowel diseases
A Piechota-Polanczyk, J Fichna - Naunyn-Schmiedeberg's archives of …, 2014 - Springer
In this review, we focus on the role of oxidative stress in the aetiology of inflammatory bowel
diseases (IBD) and colitis-associated colorectal cancer and discuss free radicals and free …
diseases (IBD) and colitis-associated colorectal cancer and discuss free radicals and free …
Opioid receptors and their ligands
A Janecka, J Fichna, T Janecki - Current topics in medicinal …, 2004 - ingentaconnect.com
This review gives a historical perspective, summarizing approximately 25 years of research
on opioids. The “typical” opioid peptides produced in the brain, “atypical” opioids encrypted …
on opioids. The “typical” opioid peptides produced in the brain, “atypical” opioids encrypted …
[HTML][HTML] Distribution, function and physiological role of melatonin in the lower gut
CQ Chen, J Fichna, M Bashashati, YY Li… - World journal of …, 2011 - ncbi.nlm.nih.gov
Melatonin is a hormone with endocrine, paracrine and autocrine actions. It is involved in the
regulation of multiple functions, including the control of the gastrointestinal (GI) system …
regulation of multiple functions, including the control of the gastrointestinal (GI) system …
[HTML][HTML] Physiology, signaling, and pharmacology of opioid receptors and their ligands in the gastrointestinal tract: current concepts and future perspectives
Opioid receptors are widely distributed in the human body and are crucially involved in
numerous physiological processes. These include pain signaling in the central and the …
numerous physiological processes. These include pain signaling in the central and the …
Beneficial effects of probiotics, prebiotics, synbiotics, and psychobiotics in inflammatory bowel disease
Inflammatory bowel disease (IBD) is a group of diseases characterized by inflammation of
the small and large intestine and primarily includes ulcerative colitis and Crohn's disease. …
the small and large intestine and primarily includes ulcerative colitis and Crohn's disease. …
[HTML][HTML] Brain-gut interactions in IBS
Irritable bowel syndrome (IBS) is a common gastrointestinal disorder with an estimated
prevalence of 10–20%. Current understanding of the pathophysiology of IBS is incomplete due to …
prevalence of 10–20%. Current understanding of the pathophysiology of IBS is incomplete due to …
[HTML][HTML] The role of morphine in regulation of cancer cell growth
K Gach, A Wyrębska, J Fichna, A Janecka - … -Schmiedeberg's archives of …, 2011 - Springer
Morphine is considered the “gold standard” for relieving pain and is currently one of the
most effective drugs available clinically for the management of severe pain associated with …
most effective drugs available clinically for the management of severe pain associated with …
Natural and synthetic α-methylenelactones and α-methylenelactams with anticancer potential
A Janecka, A Wyrębska, K Gach, J Fichna… - Drug Discovery …, 2012 - Elsevier
α-Methylene-γ- and δ-lactones, as well as α-methylene-γ- and δ-lactams, are plant-derived
compounds often used in traditional medicine for the treatment of inflammatory diseases. In …
compounds often used in traditional medicine for the treatment of inflammatory diseases. In …