User profiles for J. W. Herzig

Joachim W. Herzig

Professor at Johannes Gutenberg University
Verified email at uni-mainz.de
Cited by 1829

Ethnopharmacological evaluation of the anticonvulsant, sedative and antispasmodic activities of Lavandula stoechas L

…, F Shaheen, Q Jabeen, BS Siddiqui, JW Herzig - Journal of …, 2000 - Elsevier
Lavandula stoechas L. (Lamiaceae) has been used for a long time in traditional medicine
as an anticonvulsant and antispasmodic. The aqueous-methanolic extract of L. stoechas …

Antispasmodic Effects of Rooibos Tea (Aspalathus linearis) is Mediated Predominantly through K+‐Channel Activation

…, MN Ghayur, SF Ali, JW Herzig - Basic & clinical …, 2006 - Wiley Online Library
Rooibos tea has been widely used for abdominal spasm and diarrhoea. The aim of the
present study was to explore the possible mechanism for its use in such ailments. Its aqueous …

Association of blood group A with increased risk of coronary heart disease in the Pakistani population

JW Herzig, H Wazirali, RA Ashfaque - Pakistan Journal of Physiology, 2005 - pjp.pps.org.pk
Many reports have appeared in recent years showing an association between blood groups
and cardiovascular diseases. Clinical studies in developed countries have shown that …

Possible mechanism of selective inotropic activity of the n-butanolic fraction from Berberis aristata fruit

…, MM Kazmi, MI Choudhary, JW Herzig - … : The Vascular System, 1999 - Elsevier
Berberis aristata is an edible plant employed in South Asian traditional medicine; in particular,
its fruit is used as a tonic remedy for liver and heart. In isolated cardiac tissues, Berberis …

Activating effects of AR-L 115 BS on the Ca2+ sensitive force, stiffness and unloaded shortening velocity (Vmax) in isolated contractile structures from mammalian …

JW Herzig, K Feile, JC Rüegg - Arzneimittel-forschung, 1981 - europepmc.org
2-[(2-Methoxy-4-methylsulfinyl) phenyl]-1H-imidazo [4, 5-b] pyridine (AR-L 115 BS), a new
positive inotropic substance, is shown to have direct activating effects upon the Ca2+ …

Role of Wnt/β-catenin pathway in cardiac lineage commitment of human umbilical cord mesenchymal stem cells by zebularine and 2'-deoxycytidine

A Mirza, I Khan, A Salim, M Husain, JW Herzig - Tissue and Cell, 2022 - Elsevier
… and data analysis; Khan I contributed towards data analysis and helped in conducting
the experiments; Qazi RM helped in conducting the experiments, Husain M and Herzig J co-…

DPI 201-106, a novel cardioactive agent. Combination of cAMP-independent positive inotropic, negative chronotropic, action potential prolonging and coronary …

…, R Salzmann, R Berthold, JW Herzig… - Naunyn-Schmiedeberg's …, 1985 - Springer
… of isometric force as described by Herzig and Riiegg (1980). … -533 (Herzig et al. 1983;
Salzmann et al. 1985) whilst catecholamines and glycosides are inactive in this model (JW Herzig, …

Cyclic AMP inhibits contractility of detergent treated glycerol extracted cardiac muscle

JW Herzig, G Köhler, G Pfitzer, JC Rüegg, G Wölffle - Pflügers Archiv, 1981 - Springer
Glycerinated myocardial fibres treated with a detergent (Lubrol WX) and suspended in ATP
salt solution produce half maximum isometric tension at pCa 6.2 (at pH 6.7). After addition of …

5-Methyl-6-phenyl-1, 3, 5, 6-tetrahydro-3, 6-methano-1, 5-benzodiazocine-2, 4-dione (BA 41899): representative of a novel class of purely calcium-sensitizing agents

P Herold, JW Herzig, P Wenk, T Leutert… - Journal of medicinal …, 1995 - ACS Publications
BA 41899 (5-methyl-6-phenyl-l, 3, 5, 6-tetrahydro-3, 6-methano-l, 5-benzodiazocine-2, 4-dione,
6) is a structurally novel 1, 5-benzodiazocine derivative and represents the prototype of a …

Calcium sensitization as new principle of inotropic therapy in end-stage heart failure?

…, P Boknik, E Gams, JW Herzig… - European journal of …, 1998 - academic.oup.com
Objective: Due to shortage of donor hearts and increasing waiting-lists of patients with end-stage
heart disease, new pharmacological principles for bridging therapies are necessary. …