A Potent Nonpeptide Antagonist of the Substance P (NK1) Receptor

RM Snider, JW Constantine, JA Lowe III, KP Longo… - Science, 1991 - science.org
CP-96,345 [(2S, 3S)-cis-2-(diphenylmethyl)-N-[(2-methoxyphenyl)-methyl]-1-azabicyclo[2.2.2]octan-3-amine]
is a potent nonpeptide antagonist of the substance P (NK 1 ) receptor. CP-…

Analysis of the hypotensive action of prazosin.

JW Constantine, WK McShane, A Scriabine… - Postgraduate …, 1975 - europepmc.org
Results of animal studies indicate that the hypotensive effect of prazosin is due to vasodilatation
which is dependent on two discernible components of drug action:(1) direct relaxation of …

From Constantine to Julian

SNC Lieu, D Montserrat - … Views. A Source History. New York, 1996 - api.taylorfrancis.com
… , Christian and Byzantine sources on the reign of Constantine. The result was a number of
… is entitled From Constantine to Julian, its main focus is on the reign of Constantine and that …

The vision of Constantine

P Weiss - Journal of Roman Archaeology, 2003 - cambridge.org
… But he did make one comment:'modern interpretation, in so far as it treats his [Constantine's]
conversion as a historical phenomenon, must place itself in a positive relationship to this …

Analysis of the cardiovascular effects of 2-(2, 6-dichlorophenylamino)-2-imidazoline hydrochloride (Catapres)

JW Constantine, WK McShane - European Journal of Pharmacology, 1968 - Elsevier
JW CONSTANTINE and WK McSHANE, Analysis of the cardiovascular effects of 2-(2,6-dichlorophenylamino)
-2'imidazoline hydrochloride (Catapres), European J. Pharmacol. 4 (1968) …

N-(Methanesulfonyl)-16-phenoxyprostaglandin carboxamides: tissue-selective, uterine stimulants

…, AJ Nelson, MR Johnson, JW Constantine… - Journal of medicinal …, 1981 - ACS Publications
In an effort to develop tissue-selective prostaglandin analogues resistant to the metabolic
inactivating pathways of the natural materials, hybrid compounds modified both at Cl with a …

Pirbuterol, a selecttve beta2 adrenergic bronchodilator.

PF Moore, JW Constantine, WE Barth - Journal of Pharmacology and …, 1978 - ASPET
Pirbuterol, 2-hydroxymethyl-3-hydroxy-6-(1-hydroxy-2-tert-butylaminoethyl)pyridine, is a new
beta2 adrenergic agonist bronchodilator. Comparison of the relative potencies of pirbuterol…

The conversion of Constantine

TD Barnes - Echos du monde classique: Classical news and views, 1985 - muse.jhu.edu
… ed ited by JW Ead ie … Constantine seems to me to go astray in rejecting or dismissing,
explicitly or implicitly, two crucial propositions which are central to my interpretation of Constantine. …

Functional postsynaptic α2-but not α1-adrenoceptors in dog saphenous vein exposed to phenoxybenzamine

JW Constantine, W Lebel, R Archer - European journal of pharmacology, 1982 - Elsevier
Phenoxybenzamine greatly attenuated phenylephrine-induced contractions of dog
saphenous vein in vitro, but had less effect on contractions induced by clonidine. The …

α2-and α2-vasular adrenoceptors in the dog

JW Constantine, D Gunnell, RA Weeks - European Journal of …, 1980 - Elsevier
Prazosin inhibited contractions o isolated-electrically stimulated dog pulmonary artery
preincubated with (−)-7- 3 H-norepinephrine, but had no effect on 3 H-overflow, whereas …