Psychoactive “bath salts”: not so soothing

MH Baumann, JS Partilla, KR Lehner - European journal of pharmacology, 2013 - Elsevier
Partilla , Kurt R. Lehner … MH Baumann, MA Ayestas Jr, JS Partilla, JR Sink, AT Shulgin,
PF Daley, SD … Baumann, MH, Partilla, JS, Lehner, KR, Thorndike, EB, Hoffman, AF, Holy, M., …

Behavioral, biological, and chemical perspectives on atypical agents targeting the dopamine transporter

…, KC Schmitt, MH Baumann, JS Partilla… - Drug and alcohol …, 2015 - Elsevier
Background Treatment of stimulant-use disorders remains a formidable challenge, and the
dopamine transporter (DAT) remains a potential target for antagonist or agonist-like …

Amphetamine‐type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin

…, DV Romero, KC Rice, FI Carroll, JS Partilla - Synapse, 2001 - Wiley Online Library
A large body of evidence supports the hypothesis that mesolimbic dopamine (DA) mediates,
in animal models, the reinforcing effects of central nervous system stimulants such as …

[HTML][HTML] The designer methcathinone analogs, mephedrone and methylone, are substrates for monoamine transporters in brain tissue

MH Baumann, MA Ayestas, JS Partilla… - …, 2012 - nature.com
… , to ensure continued support, we are displaying the site without styles and JavaScript. …
John S Partilla … Michael H Baumann, Mario A Ayestas Jr, John S Partilla, Jacqueline R Sink & …

[HTML][HTML] Powerful cocaine-like actions of 3, 4-methylenedioxypyrovalerone (MDPV), a principal constituent of psychoactive 'bath salts' products

MH Baumann, JS Partilla, KR Lehner… - …, 2013 - nature.com
… ensure continued support, we are displaying the site without styles and JavaScript. …
John S Partilla … Zolkowska D, Jain R, Rothman RB, Partilla JS, Roth BL, Setola V et al (2009). …

[HTML][HTML] N-substituted piperazines abused by humans mimic the molecular mechanism of 3, 4-methylenedioxymethamphetamine (MDMA, or 'Ecstasy')

…, RD Clark, AG Budzynski, JS Partilla… - …, 2005 - nature.com
3, 4-Methylenedioxymethamphetamine (MDMA, or ‘Ecstasy’) is an illicit drug that stimulates
the release of serotonin (5-HT) and dopamine (DA) from neurons. Recent evidence reveals …

Pharmacology of novel synthetic stimulants structurally related to the “bath salts” constituent 3, 4-methylenedioxypyrovalerone (MDPV)

…, KR Antonazzo, JL Wiley, BE Blough, JS Partilla… - …, 2014 - Elsevier
There has been a dramatic rise in the abuse of synthetic cathinones known as “bath salts,”
including 3,4-methylenedioxypyrovalerone (MDPV), an analog linked to many adverse events…

Evidence for the involvement of dopamine transporters in behavioral stimulant effects of modafinil

D Zolkowska, R Jain, RB Rothman, JS Partilla… - … of Pharmacology and …, 2009 - ASPET
Modafinil is prescribed for numerous medical conditions, but the drug's mechanism of action
is unclear. Here, we examined the interaction of modafinil with receptors and transporters in …

In vitro characterization of ephedrine-related stereoisomers at biogenic amine transporters and the receptorome reveals selective actions as norepinephrine …

RB Rothman, N Vu, JS Partilla, BL Roth… - … of Pharmacology and …, 2003 - ASPET
Ephedrine is a long-studied stimulant available both as a prescription and over-the-counter
medication, as well as an ingredient in widely marketed herbal preparations, and is also …

Interaction of amphetamines and related compounds at the vesicular monoamine transporter

JS Partilla, AG Dempsey, AS Nagpal, BE Blough… - … of Pharmacology and …, 2006 - ASPET
Amphetamine-type agents interact with the vesicular monoamine transporter type 2 (VMAT
2 ), promoting the release of intravesicular neurotransmitter and an increase in cytoplasmic …