Ribonucleic acids from animal cells

JE Darnell Jr - Bacteriological reviews, 1968 - Am Soc Microbiol
INTRODUCTION One of the important branches of molecular biology at the present time isthe
study of the synthesis, structure, and function ofribonucleic acid (RNA) molecules; yet only …

[PDF][PDF] Effect of chlorpromazine, dibenamine and phenoxybenzamine on the contractile response of taenia coli to potassium, acetylcholine, angiotensin and barium

…, O Carrier, J Frankenheim, JR Darnell - Journal of Pharmacology …, 1968 - Citeseer
EFFECT OF CHLORPROMAZINE, DIBENAMINE AND ON THE CONTRACTILE RESPONSE
OF TAENIA AND assistance of Js of Pharmacology Accepted for Page 1 106 Ta Joumtu ov …

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

JE Darnell Jr, M Kerr, GR Stark - Science, 1994 - science.org
Through the study of transcriptional activation in response to interferon α (IFN-α) and interferon
γ (IFN-γ), a previously unrecognized direct signal transduction pathway to the nucleus …

Transcription units for mRNA production in eukaryotic cells and their DNA viruses

JE Darnell Jr - Progress in nucleic acid research and molecular …, 1979 - Elsevier
Publisher Summary This chapter reviews that in bacteria the rate of protein synthesis for any
specific protein is controlled by the supply of mRNA for that protein. In turn, the supply of any …

Variation in Plaque-Forming Ability among Parental and Glonal Strains of HeLa Cells.

JEJ Darnell, TK Sawyer - 1959 - cabidigitallibrary.org
2 HeLa cell lines and pure clones derived from them were compared for plaque-forming ability
when infected with type 1 poliovirus. It was found that a previously uncloned stock HeLa …

STATs and gene regulation

JE Darnell Jr - Science, 1997 - science.org
STATs (signal transducers and activators of transcription) are a family of latent cytoplasmic
proteins that are activated to participate in gene control when cells encounter various …

Maximal activation of transcription by Statl and Stat3 requires both tyrosine and serine phosphorylation

Z Wen, Z Zhong, JE Darnell Jr - Cell, 1995 - cell.com
Statl and Stat3 are latent transcriptional factors activated initially through phosphorylation
on single tyrosine residues induced by cytokine and growth factor occupation of cell surface …

Transcriptional responses to polypeptide ligands: the JAK-STAT pathway

C Schindler, JE Darnell Jr - Annual review of biochemistry, 1995 - annualreviews.org
Cytokines and growth factors regulate multiple aspects of cell growth through their interactions
with specific receptors. These receptors initiate signals di rected at both the cytoplasmic …

Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

Z Zhong, Z Wen, JE Darnell Jr - Science, 1994 - science.org
The STAT family of proteins carries out a dual function: signal transduction and activation of
transcription. A new family member, Stat3, becomes activated through phosphorylation on …

Stats: transcriptional control and biological impact

DE Levy, JE Darnell Jr - Nature reviews Molecular cell biology, 2002 - nature.com
Extracellular proteins bound to cell-surface receptors can change nuclear gene expression
patterns in minutes, with far-reaching consequences for development, cell growth and …