Human β-secretase (BACE) and BACE inhibitors

V John, JP Beck, MJ Bienkowski, S Sinha… - Journal of medicinal …, 2003 - ACS Publications
Introduction β-Secretase (BACE) is a proteolytic enzyme involved in the processing of an
integral membrane protein known as amyloid precursor protein, or APP. The proteolysis of APP …

Pharmacognosy of Mimosa tenuiflora (willd.) poiret

R Anton, Y Jiang, B Weniger, JP Beck… - Journal of …, 1993 - Elsevier
A chemical investigation of the bark of Mimosa tenuiflora (Willd.) Poiret, performed in our
laboratory, allowed the isolation and identification of three new triterpenoid saponins (…

Cytotoxic activity of Amaryllidaceae alkaloids

B Weniger, L Italiano, JP Beck, J Bastida… - Planta …, 1995 - thieme-connect.com
25 Amaryllidaceae alkaloids belonging to different skeletal types were evaluated for their
cytotoxic activity against one murine non-tumoral cell line (LMTK) and two human tumoral cell …

Valepotriates, a new class of cytotoxic and antitumor agents

C Bounthanh, C Bergmann, JP Beck… - Planta …, 1981 - thieme-connect.com
The following valepotriates: valtrate and didrovaltrate, isolated from the roots of Valeriana
wallichii DC, as well as baldrinal, a degradation product of the valtrate, were tested for their …

Fifteen years of experience with Integral-Leg-Prosthesis: Cohort study of artificial limb attachment system

DL Juhnke, JP Beck, HH Aschoff - Journal of Rehabilitation …, 2015 - search.proquest.com
Integral-Leg-Prosthesis (ILP) is a comparatively new attachment system that allows direct
skeletal docking of artificial limbs. Between January 1999 and December 2013, 69 patients …

The transformation of work revisited: The limits of flexibility in American manufacturing

SP Vallas, JP Beck - Social Problems, 1996 - academic.oup.com
Students of work processes have increasingly debated the likely emergence of a flexible, “post-Fordist”
pattern of work organization within advanced capitalist manufacturing industries. …

Percutaneous osseointegrated prostheses for amputees: Limb compensation in a 12-month ovine model

TJ Shelton, JP Beck, RD Bloebaum, KN Bachus - Journal of biomechanics, 2011 - Elsevier
Percutaneous osseointegrated prostheses are being investigated as an alternative strategy
to attach prosthetic limbs to patients. Although the use of these implants has shown to be …

[PDF][PDF] The road to recovery and rehabilitation for injured service members with limb loss: a focus on Iraq and Afghanistan.

…, PF Pasquina, JB Webster, JP Beck… - US Army Medical …, 2010 - apps.dtic.mil
The early ability to stabilize and transport injured servicemen and women from Operation
Enduring Freedom (OEF) and Operation Iraqi Freedom (OIF) to specialized military centers in …

Efficacy of a porous‐structured titanium subdermal barrier for preventing infection in percutaneous osseointegrated prostheses

S Jeyapalina, JP Beck, KN Bachus… - Journal of …, 2012 - Wiley Online Library
Infections of percutaneous osseointegrated prostheses (POP) cause prolonged morbidity and
device failure because once established, they are refractory to antibiotic therapy. To date, …

A preliminary investigation into the effects of antipsychotics on sub-chronic phencyclidine-induced deficits in attentional set-shifting in female rats

SL McLean, JP Beck, ML Woolley, JC Neill - Behavioural brain research, 2008 - Elsevier
RATIONALE: The NMDA receptor antagonist, phencyclidine (PCP), has been shown to
induce symptoms characteristic of schizophrenia. A loss in executive function and the ability to …