User profiles for J. M. Rho

Jong M. Rho

Professor of Neurosciences, Pediatrics and Pharmacology, University of California San …
Verified email at health.ucsd.edu
Cited by 14999

The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies

M Maalouf, JM Rho, MP Mattson - Brain research reviews, 2009 - Elsevier
Both calorie restriction and the ketogenic diet possess broad therapeutic potential in various
clinical settings and in various animal models of neurological disease. Following calorie …

Anticonvulsant mechanisms of the ketogenic diet

KJ Bough, JM Rho - Epilepsia, 2007 - Wiley Online Library
The ketogenic diet (KD) is a broadly effective treatment for medically refractory epilepsy.
Despite nearly a century of use, the mechanisms underlying its clinical efficacy remain unknown…

[HTML][HTML] The ketogenic diet as a treatment paradigm for diverse neurological disorders

CE Stafstrom, JM Rho - Frontiers in pharmacology, 2012 - frontiersin.org
Dietary and metabolic therapies have been attempted in a wide variety of neurological
diseases, including epilepsy, headache, neurotrauma, Alzheimer disease, Parkinson disease, …

Optimal clinical management of children receiving the ketogenic diet: recommendations of the International Ketogenic Diet Study Group

…, J Nation, DR Nordli Jr, HH Pfeifer, JM Rho… - …, 2009 - Wiley Online Library
… Kossoff, Cross, Rho, Veggiotti, and Ms. Blackford and Pfeifer have received support for … Rho
and Wheless have been on the speaker's bureau for Ortho McNeil. Dr. Wheless has been on …

Optimal clinical management of children receiving dietary therapies for epilepsy: Updated recommendations of the International Ketogenic Diet Study Group

…, JK Nathan, DR Nordli Jr, HH Pfeifer, JM Rho… - Epilepsia …, 2018 - Wiley Online Library
Ketogenic dietary therapies ( KDTs ) are established, effective nonpharmacologic treatments
for intractable childhood epilepsy. For many years KDTs were implemented differently …

Ketones inhibit mitochondrial production of reactive oxygen species production following glutamate excitotoxicity by increasing NADH oxidation

M Maalouf, PG Sullivan, L Davis, DY Kim, JM Rho - Neuroscience, 2007 - Elsevier
Dietary protocols that increase serum levels of ketones, such as calorie restriction and the
ketogenic diet, offer robust protection against a multitude of acute and chronic neurological …

The ketogenic diet increases mitochondrial uncoupling protein levels and activity

…, RC Concepcion, AK Agarwal, JM Rho - Annals of …, 2004 - Wiley Online Library
Fatty acids are known to enhance mitochondrial uncoupling protein (UCP) activity. We asked
whether a high‐fat ketogenic diet (KD) increases UCP levels and activity in hippocampi of …

Hair-cell innervation by spiral ganglion cells in adult cats

NYS Kiang, JM Rho, CC Northrop, MC Liberman… - Science, 1982 - science.org
A horseradish peroxidase technique was used to trace the peripheral terminations of two
types of ganglion cells in adult cats. It was found that large, usually bipolar ganglion cells end …

[HTML][HTML] The ketogenic diet is an effective adjuvant to radiation therapy for the treatment of malignant glioma

MG Abdelwahab, KE Fenton, MC Preul, JM Rho… - PloS one, 2012 - journals.plos.org
Introduction The ketogenic diet (KD) is a high-fat, low-carbohydrate diet that alters metabolism
by increasing the level of ketone bodies in the blood. KetoCal® (KC) is a nutritionally …

[HTML][HTML] Ketogenic diets, mitochondria, and neurological diseases

LB Gano, M Patel, JM Rho - Journal of lipid research, 2014 - ASBMB
The ketogenic diet (KD) is a broad-spectrum therapy for medically intractable epilepsy and
is receiving growing attention as a potential treatment for neurological disorders arising in …