Supplemental perioperative oxygen and the risk of surgical wound infection: a randomized controlled trial

FJ Belda, L Aguilera, JG de la Asunción, J Alberti… - Jama, 2005 - jamanetwork.com
ContextSupplemental perioperative oxygen has been variously reported to halve or double
the risk of surgical wound infection.ObjectiveTo test the hypothesis that supplemental oxygen …

A Ginkgo biloba extract (EGb 761) prevents mitochondrial aging by protecting against oxidative stress

J Sastre, A Millan, JG de la Asuncion, R Pla… - Free Radical Biology …, 1998 - Elsevier
The effect of aging on indices of oxidative damage in rat mitochondria and the protective effect
of the Ginkgo biloba extract EGb 761 was investigated. Mitochondrial DNA from brain and …

Oxidative damage to mitochondrial DNA and glutathione oxidation in apoptosis: studies in vivo and in vitro

JM Esteve, J Mompo, JG De La Asuncion… - The FASEB …, 1999 - Wiley Online Library
Free radicals may be involved in apoptosis although this is the subject of some controversy.
Furthermore, the source of free radicals in apoptotic cells is not certain. The aim of this study …

AZT treatment induces molecular and ultrastructural oxidative damage to muscle mitochondria. Prevention by antioxidant vitamins.

JG de la Asuncion, ML del Olmo… - The Journal of …, 1998 - Am Soc Clin Investig
AIDS patients who receive zidovudine (AZT) frequently suffer from myopathy. This has been
attributed to mitochondrial (mt) damage, and specifically to the loss of mtDNA. This study …

Pentoxifylline ameliorates cerulein-induced pancreatitis in rats: role of glutathione and nitric oxide

…, B Camps, JG de la Asunción… - … of Pharmacology and …, 2000 - ASPET
Reactive oxygen radicals, nitric oxide, and cytokines have been implicated in the initiation
of pancreatic tissue damage and impairment of the pancreatic microcirculation in acute …

AZT induces oxidative damage to cardiac mitochondria: protective effect of vitamins C and E

JG de la Asunción, ML Del Olmo… - Life sciences, 2004 - Elsevier
AZT (zidovudine) is a potent inhibitor of HIV replication and a major antiretroviral drug used
for AIDS treatment. A major limitation in the use of AZT is the occurrence of severe side …

Zidovudine (AZT) causes an oxidation of mitochondrial DNA in mouse liver

JG de la Asunción, ML del Olmo, J Sastre… - Hepatology, 1999 - journals.lww.com
Zidovudine (3′–azido–2′, 3′–dideoxythymidine [AZT]) inhibits human immunodeficiency
virus replication and delays progression of acquired immune deficiency syndrome. We …

Hepatic γ-cystathionase deficiency in patients with AIDS

JA Martin, J Sastre, JG de la Asunción, FV Pallardó… - Jama, 2001 - jamanetwork.com
Methods We followed the method described by Sturman et al 4 to measure γ-cystathionase
activity in liver samples obtained from autopsies of 3 men with the acquired …

Serum levels of clusterin, PKR, and RAGE correlate with amyloid burden in Alzheimer's disease

…, MC Badia, JG de la Asuncion… - Journal of …, 2021 - content.iospress.com
Background: Alzheimer’s disease (AD) is the most common form of dementia and biomarkers
are essential to help in the diagnosis of this disease. Image techniques and cerebrospinal …

Hepatic amino acid uptake is decreased in lactating rats. In vivo and in vitro studies

JG de la Asunción, A Devesa, JR Vińa, T Barber - The Journal of Nutrition, 1994 - Elsevier
To study the redistribution of amino acids to the mammary gland during lactation we used
lactating and virgin rats fed liquid diets. Virgin rats were divided in two groups: one group was …