Transgenic angiopoietin-like (angptl) 4 overexpression and targeted disruption of angptl4 and angptl3: regulation of triglyceride metabolism
…, D Li, Y Qiu, CC Fraser, DD Yang, JG Heuer… - …, 2005 - academic.oup.com
Lipoprotein lipase (LPL) is a key regulator of triglyceride clearance. Its coordinated regulation
during feeding and fasting is critical for maintaining lipid homeostasis and energy supply. …
during feeding and fasting is critical for maintaining lipid homeostasis and energy supply. …
Adoptive transfer of in vitro-stimulated CD4+ CD25+ regulatory T cells increases bacterial clearance and improves survival in polymicrobial sepsis
JG Heuer, T Zhang, J Zhao, C Ding… - The Journal of …, 2005 - journals.aai.org
Regulatory CD4+ CD25+ T cells (Tregs) suppress autoimmune and inflammatory diseases
through mechanisms that are only partly understood. Previous studies suggest that Tregs can …
through mechanisms that are only partly understood. Previous studies suggest that Tregs can …
FGF21 Is Increased by Inflammatory Stimuli and Protects Leptin-Deficient ob/ob Mice from the Toxicity of Sepsis
KR Feingold, C Grunfeld, JG Heuer, A Gupta… - …, 2012 - academic.oup.com
The acute phase response (APR) produces marked alterations in lipid and carbohydrate
metabolism including decreasing plasma ketone levels. Fibroblast growth factor 21 (FGF21) is …
metabolism including decreasing plasma ketone levels. Fibroblast growth factor 21 (FGF21) is …
The Drosophila homeotic target gene centrosomin (cnn) encodes a novel centrosomal protein with leucine zippers and maps to a genomic region required for …
JG Heuer, K Li, TC Kaufman - Development, 1995 - journals.biologists.com
… Heuer, unpublished observations) and it is in this posterior ANTP low region that CNN is
accumulated. Thus, the negative regulation of cnn by Antp is apparently dependent on high …
accumulated. Thus, the negative regulation of cnn by Antp is apparently dependent on high …
Expression of nerve growth factor (NGF) receptors in the developing inner ear of chick and rat
CSV Bartheld, SL Patterson, JG Heuer… - …, 1991 - journals.biologists.com
The expression of nerve growth factor receptors (NGFRs) was studied in the developing
inner ear with in situ hybridization in chick embryos and with immunocytochemistry in rat …
inner ear with in situ hybridization in chick embryos and with immunocytochemistry in rat …
Structure and developmental expression of the chicken NGF receptor
JG Heuer, S Fatemie-Nainie, EF Wheeler… - Developmental …, 1990 - Elsevier
The nucleotide and deduced amino acid sequence of a cDNA clone of the chicken NGF
receptor (NGFR) is reported and is compared with sequences of mammalian NGF receptors. A …
receptor (NGFR) is reported and is compared with sequences of mammalian NGF receptors. A …
Development of a long‐acting relaxin analogue, LY3540378, for treatment of chronic heart failure
…, SO Nwosu, MC Carr, JG Heuer… - British Journal of …, 2023 - Wiley Online Library
Background and Purpose Chronic heart failure, a progressive disease with limited treatment
options currently available, especially in heart failure with preserved ejection fraction (…
options currently available, especially in heart failure with preserved ejection fraction (…
Evaluation of protein C and other biomarkers as predictors of mortality in a rat cecal ligation and puncture model of sepsis
JG Heuer, GR Sharma, B Gerlitz, T Zhang… - Critical care …, 2004 - journals.lww.com
Objective: To evaluate protein C and other factors associated with the septic response as
predictors of mortality in a clinically relevant animal model of sepsis. Design: Laboratory …
predictors of mortality in a clinically relevant animal model of sepsis. Design: Laboratory …
Myostatin neutralization results in preservation of muscle mass and strength in preclinical models of tumor-induced muscle wasting
…, KM Credille, VJ Wroblewski, BK Lin, JG Heuer - Molecular Cancer …, 2015 - AACR
Skeletal muscle wasting occurs in a great majority of cancer patients with advanced disease
and is associated with a poor prognosis and decreased survival. Myostatin functions as a …
and is associated with a poor prognosis and decreased survival. Myostatin functions as a …
Alternating phases of FGF receptor and NGF receptor expression in the developing chicken nervous system
JG Heuer, CS von Bartheld, Y Kinoshita, PC Evers… - Neuron, 1990 - cell.com
Patterns of expression of transcripts encoding receptors for fibroblast growth factor and nerve
growth factor (FGF-R and NGF-R) in the developing chick nervous system are compared …
growth factor (FGF-R and NGF-R) in the developing chick nervous system are compared …