Recently endothelium-derived relaxing factor (EDRF) has been identified as nitric oxide.
The source of the nitric oxide is l-arginine, and the l-arginine-nitric oxide pathway has been …

… Odrcich MJ, Graham CH, Kimura KA, McLaughlin BE, Marks GS, Nakatsu K, and Brien JF.
Heme oxygenase and nitric oxide synthase in the placenta of the guinea-pig during gestation. …

Data from human and experimental animal research indicate that nitric oxide (NO), a novel
messenger, formed during the nitric oxide synthase-catalyzed oxidation of L-arginine to L-…

Studies on the physiological role of heme oxygenase (HO) require an inhibitor that will
selectively inhibit HO activity without inhibiting the activity of either nitric oxide synthase (NOS) or …

… Brien b , Kanji Nakatsu b , Walter A. Szarek a … Brian McLaughlin for assistance with the
biological evaluations. … , HJ Vreman, DK Stevenson, JF Brien, K. Nakatsu, DH Maurice, GS Marks …

The distribution of the antiarrhythmic drug amiodarone and its principal lipophilic metabolite,
desethylamiodarone, was determined in postmortem tissues of six patients who received …

The disposition of ethanol and acetaldehyde in maternal venous blood and amniotic fluid
was studied over 3.5 hours following the ingestion of 0.3 gm/kg of ethanol by six healthy …

In the hippocampus, the CA1 region is selectively vulnerable to the effects of chronic prenatal
ethanol exposure. In the guinea‐pig, the number of CA1 pyramidal cells is decreased after …

AMIODARONE, an iodine-containing benzofuran derivative, has been widely available in
Europe for over 15 years, but its use in North America is still experimental. The drug has potent …

Haem oxygenases (HO) are involved in the catalytic breakdown of haem to generate carbon
monoxide (CO), iron and biliverdin. It is widely accepted that products of haem catabolism …