Recent progress of wavelength selective switch

…, L Stewart, J Armstrong, IG Clarke… - Journal of Lightwave …, 2020 - ieeexplore.ieee.org
Wavelength Division Multiplexing (WDM) networks with reconfigurable optical add/drop
multiplexers (ROADMs) realize automatic scheduling and restoration at the wavelength level …

Temperature-stable spun elliptical-core optical-fiber current transducer

IG Clarke - Optics letters, 1993 - opg.optica.org
A temperature-stable electrical current transducer, with a spun birefringent elliptical-core
optical fiber, has been designed, theoretically analyzed, constructed, and tested. The …

Design and performance of a stable linear retarder

…, AH Rose, PA Williams, CM Wang, IG Clarke… - Applied …, 1997 - opg.optica.org
The National Institute of Standards and Technology (NIST) has developed a nominally
quarter-wave linear retarder for wavelengths near 1.3 µm that is stable within ±0.1 retardance …

Sequence conservation in Ig-like domains: the role of highly conserved proline residues in the fibronectin type III superfamily

A Steward, S Adhya, J Clarke - Journal of molecular biology, 2002 - Elsevier
Ig-like domains were correct, then we would expect to see similar conservation of proline
residues at the domain boundaries in other Ig… A or G strands of Ig domains. However, three high…

THE BIOLOGICAL ASSAY OF HISTAMINE AND DIPHENHY-DRAMINE HYDROCHOLRIDE (BENADRYL-HYDROCHLORIDE)

G Chen, CR Ensor, IG Clarke - Journal of Pharmacology and Experimental …, 1948 - ASPET
A simple and rapid method of biological assay of histamine and Benadryl·HCl in vitro using
isolated guinea pigs' ileum is presented. The linear relationship between dose and effect in …

Eliptically polarizing optical fiber

…, M Bjarme, D Chan, IG Clarke… - Fiber Optic Sensor …, 1999 - spiedigitallibrary.org
Elliptically polarizing optical fiber has been fabricated. Measurements show an extinction of
the lossy mode relative to the transmitted mode of around 10 dB/m. The preform is spun …

Central nervous action of hydantoins, oxazolidinediones and thiazolidones

G CHEN, CR ENSOR, IG CLARKE - AMA Archives of Neurology …, 1951 - jamanetwork.com
THAT SEIZURE electroencephalographic patterns may be observed during sleep or by
pentylenetetrazole (metrazol®) activation in epileptic patients with normal routine …

Mechanical unfolding of a titin Ig domain: structure of transition state revealed by combining atomic force microscopy, protein engineering and molecular dynamics …

…, JLT Herrera, A Steward, E Paci, J Clarke - Journal of molecular …, 2003 - Elsevier
… We suggest, however, that the correlation between unfolding rates of different titin Ig domains
and their resistance to force is not coincidental: it is the same region of the protein that is …

Mechanical unfolding of a titin Ig domain: structure of unfolding intermediate revealed by combining AFM, molecular dynamics simulations, NMR and protein …

…, A Steward, E Paci, M Karplus, J Clarke - Journal of molecular …, 2002 - Elsevier
The mechanical unfolding of an immunoglobulin domain from the human muscle protein titin
(TI I27) has been shown to proceed via a metastable intermediate in which the A-strand is …

Folding pathway of an Ig domain is conserved on and off the ribosome

…, R Beckmann, G Von Heijne, J Clarke… - Proceedings of the …, 2018 - National Acad Sciences
… Here, we investigate the cotranslational folding of an all-β Ig domain, titin I27. Using an
arrest peptide-based assay and structural studies by cryo-EM, we show that I27 folds in the …