[HTML][HTML] IASLC multidisciplinary recommendations for pathologic assessment of lung cancer resection specimens after neoadjuvant therapy

…, JM Goo, J Heymach, FR Hirsch, H Horinouchi… - Journal of Thoracic …, 2020 - Elsevier
… Erasmus MD m , Carlos Gil Ferreira MD n , Jin-Mo Goo MD o , John Heymach MD, PhD h ,
Fred R. Hirsch MD p , Hidehito Horinouchi MD q , Keith Kerr MD r , Mark Kris MD i … Yasushi …

Review of hemoglobin‐vesicles as artificial oxygen carriers

H Sakai, K Sou, H Horinouchi, K Kobayashi… - Artificial …, 2009 - Wiley Online Library
… of the catalase-like activity provided by metHb and l-tyrosine, which eliminates H 2 O 2 , a
by-product of Hb autoxidation. … However, two of eight rats in the rHSA group died before 6 h. …

Haemoglobin‐vesicles as artificial oxygen carriers: present situation and future visions

H Sakai, K Sou, H Horinouchi… - Journal of internal …, 2008 - Wiley Online Library
During the long history of development of haemoglobin (Hb)‐based O 2 carriers (HBOCs),
many side effects of Hb molecules have become apparent. They imply the physiological …

Phase II clinical study of photodynamic therapy using mono-L-aspartyl chlorin e6 and diode laser for early superficial squamous cell carcinoma of the lung

…, T Yana, K Matsui, T Shiraishi, H Horinouchi - Lung cancer, 2003 - Elsevier
… (T1/2ß) of approximately 134 h [20] which agrees with the data of our phase I study [6], which
is much shorter than the approximately 250 h of Photofrin. NPe6 is eliminated almost twice …

[HTML][HTML] DOCK2 is involved in the host genetics and biology of severe COVID-19

…, I Hase, S Yoshida, S Suzuki, M Kawada, H Horinouchi… - Nature, 2022 - nature.com
Identifying the host genetic factors underlying severe COVID-19 is an emerging challenge 1
, 2 , 3 , 4 – 5 . Here we conducted a genome-wide association study (GWAS) involving 2,393 …

[HTML][HTML] Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population

…, H Nakayama, S Matsumoto, H Horinouchi… - Nature …, 2023 - nature.com
Lung adenocarcinoma is the most common type of lung cancer. Known risk variants explain
only a small fraction of lung adenocarcinoma heritability. Here, we conducted a two-stage …

Alectinib in Resected ALK-Positive Non–Small-Cell Lung Cancer

…, DH Lee, JS Lee, W Zhong, H Horinouchi… - … England Journal of …, 2024 - Mass Medical Soc
Background Platinum-based chemotherapy is the recommended adjuvant treatment for patients
with resectable, ALK-positive non–small-cell lung cancer (NSCLC). Data on the efficacy …

Immunohistochemical status of PD-L1 in thymoma and thymic carcinoma

Y Katsuya, Y Fujita, H Horinouchi, Y Ohe, S Watanabe… - Lung Cancer, 2015 - Elsevier
… After rinsing with H 2 O, the sections were incubated in 3% peroxidase and washed with H
2 O, followed by buffer. For staining, sections were exposed to the primary antibodies, PD-L1 (…

Frequency of transmission of human parvovirus B19 infection by fibrin sealant used during thoracic surgery

…, M Sawafuji, M Watanabe, H Horinouchi… - The Annals of thoracic …, 2002 - Elsevier
Background. Fibrin sealant is used in many kinds of surgical procedures. Although pasteurization
is insufficient to remove human parvovirus (HPV) B19 from this plasma-derived product…

Reliability of small biopsy samples compared with resected specimens for the determination of programmed death-ligand 1 expression in non–small-cell lung cancer

…, H Utsumi, S Kanda, H Horinouchi, H Nokihara… - Clinical lung cancer, 2015 - Elsevier
Background Several studies have assessed the expression of programmed death-ligand 1 (PD-L1)
in resected surgical specimens of non–small-cell lung cancer (NSCLC). However, …