User profiles for H. Gurdal

Hakan Gurdal

- Verified email at medicine.ankara.edu.tr - Cited by 1432

HATİCE GÜRDAL

- Verified email at istanbul.edu.tr - Cited by 152

Effects of Diabetes on Ryanodine Receptor Ca Release Channel (RyR2) and Ca2+ Homeostasis in Rat Heart

N Yaras, M Ugur, S Ozdemir, H Gurdal, N Purali… - Diabetes, 2005 - Am Diabetes Assoc
… Our data also show that insulin incubation of the cardiomyocytes from diabetic rats for 4 h
significantly restored the altered parameters of Ca 2+ sparks and thus provides support for the …

[HTML][HTML] Immunological analysis of a CCHFV mRNA vaccine candidate in mouse models

T Aligholipour Farzani, K Földes, K Ergünay, H Gurdal… - Vaccines, 2019 - mdpi.com
… The mix was incubated at 37 C for 2 h. This kit provides a 5′-cap by using 5′-Anti-Reverse
Cap Analog (ARCA) and 50–100 poly (A)-tail in addition to the in vitro transcription. Finally, …

miR-770-5p regulates EMT and invasion in TNBC cells by targeting DNMT3A

S Noyan, AA Ozketen, H Gurdal, BG Dedeoglu - Cellular Signalling, 2021 - Elsevier
… After 48 h, cells were harvested for the assay of qRT-PCR and after 72 h cells were harvested
for Western blotting. Each experiment was repeated independently at least three times. …

α1‐Adrenoceptor‐mediated contraction of rat aorta is partly mediated via transactivation of the epidermal growth factor receptor

N Ulu, H Gurdal, SW Landheer, M Duin… - British journal of …, 2010 - Wiley Online Library
Background and purpose: High level of plasma catecholamines is a risk factor for vascular
diseases such as hypertension and atherosclerosis. Catecholamines induce hypertrophy of …

[HTML][HTML] Overexpression of β-Arrestins inhibits proliferation and motility in triple negative breast cancer cells

SY Bostanabad, S Noyan, BG Dedeoglu, H Gurdal - Scientific reports, 2021 - nature.com
… 48 h at 37 C, the medium was replaced, and the cells were cultured for an additional 12 h. …
For the cell invasion assay, cells were incubated for 4 h in serum free medium and a total of …

Inverse agonist properties of dopaminergic antagonists at the D1A dopamine receptor: uncoupling of the D1Adopamine receptor from Gs protein

G Cai, H Gurdal, C Smith, HY Wang, E Friedman - Molecular Pharmacology, 1999 - ASPET
… binding and dissociation constants for the D 1A dopamine receptor, using the ligand [ 125
I]SCH23982 were 0.38 ± 0.09 nM and 1 to 4 pmol/mg, respectively, when assessed 48 h after …

[HTML][HTML] Involvement of miR-770-5p in trastuzumab response in HER2 positive breast cancer cells

S Noyan, H Gurdal, B Gur Dedeoglu - PLoS One, 2019 - journals.plos.org
… After an incubation period of 48 h or 72 h, cells were harvested using a cell scraper in ice-cold
PBS. The RNA and protein were isolated for further qPCR and western blot analysis …

Balneological outpatient treatment for patients with knee osteoarthritis; an effective non-drug therapy option in daily routine?

K Özkuk, H Gürdal, M Karagülle, Y Barut… - International journal of …, 2017 - Springer
This study aims to compare the effects of balneological treatments applied at consecutive
and intermittent sessions without interfering with their daily routine in patients with knee …

[HTML][HTML] Partial agonistic effect of cetuximab on epidermal growth factor receptor and Src kinase activation in triple‑negative breast cancer cell lines

H Gurdal, MM Tuglu… - … journal of oncology, 2019 - spandidos-publications.com
… -24 h, the medium in each well was replaced with serum-free medium and incubated for 4 h
… CTX or EGF was then added to the wells and impedance was recorded for 24 h. The results …

The effect of long-term resveratrol treatment on relaxation to estrogen in aortae from male and female rats: role of nitric oxide and superoxide

S Soylemez, H Gurdal, A Sepici, F Akar - Vascular Pharmacology, 2008 - Elsevier
Resveratrol, which is found in several foods, has vasorelaxing and estrogen-like activities.
The aim of the present study was to determine whether the relaxation to estrogen is differently …