Materials and Methods Animals and drugs. Male CD1 mice weighing 18 to 24 g and male
Sprague-Dawley rats were obtained from Charles River (St. Aubin-les-Elbeuf, France). …

… -like action of SL651498 (10 mg/kg, po) indicated that the effects lasted for more than 3 h in
… SL651498 or diazepam was given simultaneously with isoniazid (800 mg/kg, sc) 42 h after …

We report here that carbamazepine and phenytoin, two widely used antiepileptic drugs,
potentiate gamma-aminobutyric acid (GABA)-induced Cl- currents in human embryonic kidney …

… for the 3 H-diazepam binding site in the rat cerebellum, while it is only weakly active at
inhibiting 3 H-Ro 5-4864 binding to the rat kidney. The potency of zolpidem at displacing 3 H-Ro …

… After an adaptation night (N-0), each volunteer underwent 5 polysomnographic recordings
at 48 h intervals. The first night (Nl) was under basal conditions, whereas in the following 4 …

Summarizes the pharmacology of the non-benzodiazepine hypnotic, zolpidem, and its
interaction with gamma aminobutyric acid A receptors in the central nervous system. Topics …

… Cytosine β-d-arabinoside (1 μM) was added 48 h after seeding to prevent the replication of
non-neuronal cells. The coverslips were transferred to the experimental chambers for patch-…

Befloxatone, a novel oxazolidinone derivative, is a potent, selective and reversible
monoamine oxidase A (MAO-A) inhibitor in vitro (K iA =1.9–3.6 nM) and ex vivo (ED 50 MAO-A=0.02 …

Progabide, a new antiepileptic GABA agonist of moderate affinity for GABA receptors, has
been studied in a number of psychiatric disorders and the results compared with the action of …

We have studied the effects of a variety of N-methyl-d-aspartate (NMDA) antagonists acting
at different sites of the NMDA receptor complex on NMDA-induced currents in Xenopus …