Immune response in mice that lack the interferon-γ receptor

…, W Hendriks, A Althage, S Hemmi, H Bluethmann… - Science, 1993 - science.org
… were MC57G cells (H-2i) either uninfected or … Gresser for natural murine IFN-a/0; H.
Hengartner and HP Pircher for antibodies to lymphocyte surface antigens; HR Bueler, J. Le, L. …

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

H Büeler, M Fischer, Y Lang, H Bluethmann, HP Lipp… - Nature, 1992 - nature.com
… Ceils were plated onto ten 90-mm feeder plates and 0.3 mg G418 per ml was added after 24
h. After 10–12 days, G418-resistant colonies were picked and placed into individual wells of …

Impaired immune and acute-phase responses in interleukin-6-deficient mice

…, M Lamers, T Kishimoto, R Zinkernagel, H Bluethmann… - Nature, 1994 - nature.com
… Shifting cells from 29 to 16 C leads to an increase in Arm levels within 3 h after temperature
shift, reaching maximum levels between 5 and 8 h (left). When cells were returned from 16 to …

Mice lacking the tumour necrosis factor receptor 1 are resistant to IMF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes

…, A Althage, R Zinkernagel, M Steinmetz, H Bluethmann - Nature, 1993 - nature.com
… o-GalN-sensitized control mice died 6-9 h after LPS challenge, cytokine-treated control
mice 7 h after challenge. Mortality of non-sensitized mice was recorded over 4 days after …

erratum: Benzodiazepine actions mediated by specific γ-aminobutyric acidA receptor subtypes

…, JM Fritschy, JR Martin, H Bluethmann, H Möhler - Nature, 2000 - nature.com
… The latency for reentering the dark compartment 24 h later was shortened in wildtype (U ¼
… the latency to re-enter the dark compartment 24 h after training in wild-type mice but not in 1(…

Molecular and neuronal substrate for the selective attenuation of anxiety

…, JM Fritschy, T Rülicke, H Bluethmann, H Möhler… - Science, 2000 - science.org
… 10 nM [ 3 H]Ro15-4513 in the presence of 100 μM diazepam to reveal the diazepam-insensitive
[ 3 H]Ro15-4513 binding sites. In wild-type mice, diazepam-insensitive [ 3 H]Ro15-4513 …

Disruption of the murine IL-4 gene blocks Th2 cytokine responses

…, GL Gros, M Bachmann, MC Lamers, H Bluethmann… - Nature, 1993 - nature.com
… -CD3 and ll -2 for 24 h. Supernatants of the last 24 h of culture were assayed for cytokines
ll-3… After 40 h, cells were labelled for 6 h using 200 p.Ci "S-methionine with or without 10 g ml* …

Attenuation of allergic airway inflammation in IL‐4 deficient mice

…, RA Pauwels, H Bluethmann - Clinical & …, 1994 - Wiley Online Library
To investigate the role of IL‐4 in vivo in allergic asthma, we developed a murine model of
allergen‐induced airway inflammation. Repealed daily exposures of actively immunised C57BL…

Amyloid-β and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice

…, F Meier, L Ozmen, H Bluethmann… - Proceedings of the …, 2009 - National Acad Sciences
Alzheimer's disease (AD) is characterized by amyloid-beta (Aβ)-containing plaques,
neurofibrillary tangles, and neuron and synapse loss. Tangle formation has been reproduced in …

Benzodiazepine-insensitive mice generated by targeted disruption of the gamma 2 subunit gene of gamma-aminobutyric acid type A receptors.

…, Y Lang, H Bluethmann, H Mohler… - Proceedings of the …, 1995 - National Acad Sciences
Vigilance, anxiety, epileptic activity, and muscle tone can be modulated by drugs acting at
the benzodiazepine (BZ) site of gamma-aminobutyric acid type A (GABAA) receptors. In vivo, …