Bartter-and Gitelman-like syndromes: salt-losing tubulopathies with loop or DCT defects
HW Seyberth, KP Schlingmann - Pediatric nephrology, 2011 - Springer
… stems from the pediatricians and neonatologists Ohlssen and Seyberth [9, 10], who
highlighted the antenatal onset of the disease. Seyberth instituted the life-saving treatment with …
highlighted the antenatal onset of the disease. Seyberth instituted the life-saving treatment with …
An improved terminology and classification of Bartter-like syndromes
HW Seyberth - Nature clinical practice Nephrology, 2008 - nature.com
… E syndrome, who were later found to have loss-of-function mutations of the genes that
encode the ROMK or furosemide-sensitive NKCC2 channels in the loop of Henle (HW Seyberth, …
encode the ROMK or furosemide-sensitive NKCC2 channels in the loop of Henle (HW Seyberth, …
Salt handling in the distal nephron: lessons learned from inherited human disorders
…, S Waldegger, HW Seyberth - American Journal …, 2005 - journals.physiology.org
… To emphasize the obviously critical role of PGE 2 in the pathogenesis of this distinct
tubular disorder, Seyberth (102) coined the term hyperprostaglandin E syndrome (HPS). …
tubular disorder, Seyberth (102) coined the term hyperprostaglandin E syndrome (HPS). …
Hypomagnesemia with secondary hypocalcemia is caused by mutations in TRPM6, a new member of the TRPM gene family
…, S Nielsen, M Sassen, S Waldegger, HW Seyberth… - Nature …, 2002 - nature.com
Magnesium is an essential ion involved in many biochemical and physiological processes.
Homeostasis of magnesium levels is tightly regulated and depends on the balance between …
Homeostasis of magnesium levels is tightly regulated and depends on the balance between …
Pharmacokinetics of different routes of administration of misoprostol
OS Tang, H Schweer, HW Seyberth… - Human …, 2002 - academic.oup.com
BACKGROUND: The pharmacokinetic parameters of four different routes of administration
of a single dose of 400 μg of misoprostol were studied. METHODS: A total of 40 women …
of a single dose of 400 μg of misoprostol were studied. METHODS: A total of 40 women …
Localization of cyclooxygenase-1 and-2 in adult and fetal human kidney: implication for renal function
…, HJ Grone, T Klein, HW Seyberth… - American Journal …, 1997 - journals.physiology.org
To gain insight into the roles of cyclooxygenase (COX)-1 and -2 in human kidney, we
analyzed their expressions and localization in adult and fetal normal kidney. Immunohistology …
analyzed their expressions and localization in adult and fetal normal kidney. Immunohistology …
Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia
…, MC Sassen, HW Seyberth… - Proceedings of the …, 2004 - National Acad Sciences
Impaired magnesium reabsorption in patients with TRPM6 gene mutations stresses an
important role of TRPM6 (melastatin-related TRP cation channel) in epithelial magnesium …
important role of TRPM6 (melastatin-related TRP cation channel) in epithelial magnesium …
Novel paracellin-1 mutations in 25 families with familial hypomagnesemia with hypercalciuria and nephrocalcinosis
…, V Tasic, F Manz, K Schärer, HW Seyberth… - Journal of the …, 2001 - journals.lww.com
Abstract. Familial hypomagnesemia with hypercalciuria and nephrocalcinosis (FHHNC) is
an autosomal recessive tubular disorder that is frequently associated with progressive renal …
an autosomal recessive tubular disorder that is frequently associated with progressive renal …
Clinical presentation of genetically defined patients with hypokalemic salt-losing tubulopathies
…, G ünter Klaus, M Konrad, HW Seyberth - The American journal of …, 2002 - Elsevier
PURPOSE: Hypokalemic salt-losing tubulopathies (Bartter-like syndromes) comprise a set
of clinically and genetically distinct inherited renal disorders. Mutations in four renal …
of clinically and genetically distinct inherited renal disorders. Mutations in four renal …
[HTML][HTML] Salt wasting and deafness resulting from mutations in two chloride channels
…, SC Reinalter, M Holder, HW Seyberth… - … England Journal of …, 2004 - Mass Medical Soc
Mutations in genes encoding chloride transporters cause Bartter's syndrome. An antenatal
form associated with salt wasting and deafness has been observed in persons with mutations …
form associated with salt wasting and deafness has been observed in persons with mutations …