Cyclic nucleotide phosphodiesterase activity, expression, and targeting in cells of the cardiovascular system

DH Maurice, D Palmer, DG Tilley, HA Dunkerley… - Molecular …, 2003 - ASPET
… (HA Dunkerley, DH Maurice, and B. Bennett, unpublished data). How these data relate to
the development of tolerance to nitroglycerin, and previous reports of elevated levels of …

[HTML][HTML] Expression of phosphodiesterase 4D (PDE4D) is regulated by both the cyclic AMP-dependent protein kinase and mitogen-activated protein kinase signaling …

…, D Palmer, SL Jimmo, DG Tilley, HA Dunkerley… - Journal of Biological …, 2000 - ASBMB
Multiple families of cyclic nucleotide phosphodiesterases (PDE) have been described, and
the regulated expression of these genes in cells is complex. Although cAMP is known to …

Reduced phosphodiesterase 3 activity and phosphodiesterase 3A level in synthetic vascular smooth muscle cells: implications for use of phosphodiesterase 3 …

HA Dunkerley, DG Tilley, D Palmer, H Liu… - Molecular …, 2002 - ASPET
Vascular smooth muscle cells (VSMC) in situ function to control contraction and are said to
express a contractile phenotype. However, during development or in response to vascular …

Altered phosphodiesterase 3-mediated cAMP hydrolysis contributes to a hypermotile phenotype in obese JCR: LA-cp rat aortic vascular smooth muscle cells …

…, SL Jimmo, D Palmer, DG Tilley, HA Dunkerley… - Diabetes, 2002 - Am Diabetes Assoc
Cardiovascular diseases represent a significant cause of morbidity and mortality in diabetes.
Of the many animal models used in the study of non-insulin-dependent (type 2) diabetes, …

Inhibition of phosphodiesterase 5 selectively reverses nitrate tolerance in the venous circulation

JD MacPherson, TD Gillespie, HA Dunkerley… - … of Pharmacology and …, 2006 - ASPET
An important component of the antianginal efficacy of glyceryl trinitrate (GTN) is attributable
to its selective venodilator effect, resulting in decreased cardiac preload and myocardial …

[BOOK][B] Differential Cyclic Nucleotide Phosphodiesterase 3 Expression in Contractile and Synthetic Vascular Smooth Muscle Cells

HA Dunkerley - 2002 - library-archives.canada.ca
Reocclusion of coronary arteries after angioplasty is a severe complication of ballooning in
which migration and proliferation of vascular smooth muscle cells (VSMC) results in …

Efficiency of the reformulated Gash's interception model in semiarid afforestations

…, JT Van Stan II, TG Pypker, D Dunkerley - Agricultural and Forest …, 2015 - Elsevier
Interception loss (I) can remove substantial portions of water from forested watersheds. Thus,
I prediction models are crucial if we are to balance human and ecosystem water needs …

Trade-off between surface runoff and soil erosion during the implementation of ecological restoration programs in semiarid regions: A meta-analysis

YF Liu, D Dunkerley, M López-Vicente, ZH Shi… - Science of the Total …, 2020 - Elsevier
… The spatial scale of the published studies ranged from 0.091 m 2 to 2.8 ha, but the
majority were conducted at a scale smaller than 100 m 2 . The study sites generally had >50% …

The fuscous honeyeater: food resources and the bird community

GM Dunkerley, H Ford, W Danthanarayana - 1990 - rune.une.edu.au
… was 245 individuals/ha, and the density of mistletoes was 4.8 individuals/ha. Birds were …
20 birds/ha. Fuscous were the most common species of bird in Eastwood ( nearly 4/ha ). They …

[HTML][HTML] A modified RUSLE model to simulate soil erosion under different ecological restoration types in the loess hilly area

G Gao, Y Liang, J Liu, D Dunkerley, B Fu - International Soil and Water …, 2023 - Elsevier
… The event soil loss (A e , t ha −1 ) is calculated as follows:(1) A e = R e K L S C P where R e
is the erosivity factor at event scale (MJ mm ha −1 h −1 ), K is the soil erodibility factor (th MJ −…