Role of platelet-activating factor in cardiovascular pathophysiology

G Montrucchio, G Alloatti… - Physiological …, 2000 - journals.physiology.org
… by a G protein (310). Although researchers believe that PAF is coupled to PLC and PLA 2
through a G protein, the G … and activates the associated G protein by exchanging guanosine …

[HTML][HTML] Platelets, diabetes and myocardial ischemia/reperfusion injury

I Russo, C Penna, T Musso, J Popara, G Alloatti… - Cardiovascular …, 2017 - Springer
… activates complex cascades including membrane G-protein, growth factor receptors, signalling
enzymes, such as nitric oxide synthase (NOS), protein kinase C and G (PKC and PKG), …

[HTML][HTML] Regulation of STAT3 and its role in cardioprotection by conditioning: focus on non-genomic roles targeting mitochondrial function

S Comitą, S Femmino, C Thairi, G Alloatti… - Basic research in …, 2021 - Springer
Ischemia–reperfusion injury (IRI) is one of the biggest challenges for cardiovascular
researchers given the huge death toll caused by myocardial ischemic disease. Cardioprotective …

Activity profile in elite Italian soccer team

…, C Gaudino, I Rogowski, G Alloatti… - … journal of sports …, 2010 - thieme-connect.com
The purpose of this study was to analyse the activity profile of players in a top-class team in
the Italian national football league over the course of a season (n= 388). The effect of playing …

Oxidative stress triggers cardiac fibrosis in the heart of diabetic rats

M Aragno, R Mastrocola, G Alloatti, I Vercellinatto… - …, 2008 - academic.oup.com
Diabetic cardiomyopathy is characterized by myocyte loss and myocardial fibrosis, leading
to decreased elasticity and impaired contractile function. The study examines the …

Cardiac effects of ghrelin and its endogenous derivatives des-octanoyl ghrelin and des-Gln14-ghrelin

I Bedendi, G Alloatti, A Marcantoni, D Malan… - European journal of …, 2003 - Elsevier
The mechanisms underlying the cardiac activities of synthetic growth hormone secretagogues
(GHS) are still unclear. The natural ligand of the GHS receptors, ie ghrelin, classically …

[HTML][HTML] Pharmacological inhibition of NLRP3 inflammasome attenuates myocardial ischemia/reperfusion injury by activation of RISK and mitochondrial pathways

…, F Chiazza, L Serpe, D Collotta, G Alloatti… - … Medicine and Cellular …, 2016 - hindawi.com
… Male Wistar rats (Harlan Laboratories, Udine, Italy) 5-6 months old, reaching a body weight
of 450–550 g, were cared in compliance with the European Directive 2010/63/EU on the …

Obestatin affords cardioprotection to the ischemic-reperfused isolated rat heart and inhibits apoptosis in cultures of similarly stressed cardiomyocytes

G Alloatti, E Arnoletti, E Bassino… - American Journal …, 2010 - journals.physiology.org
… Gallo MP , Levi R , Ramella R , Brero A , Boero O , Tota B , Alloatti G. Endothelium-derived
nitric oxide mediates the antiadrenergic effect of human vasostatin-1 in rat ventricular …

Catestatin reduces myocardial ischaemia/reperfusion injury: involvement of PI3K/Akt, PKCs, mitochondrial KATP channels and ROS signalling

…, MC Cerra, T Angelone, B Tota, G Alloatti… - … -European Journal of …, 2013 - Springer
… Adult rats were anaesthetized by ip injection of urethane (1 g/kg) and killed by decapitation.
… adjusting the coronary flow to 9 ± 1 ml/min/g, and an end-diastolic LVP (LVEDP) of about 5 …

[HTML][HTML] Catestatin improves post-ischemic left ventricular function and decreases ischemia/reperfusion injury in heart

C Penna, G Alloatti, MP Gallo, MC Cerra, R Levi… - Cellular and molecular …, 2010 - Springer
The Chromogranin A (CgA)-derived anti-hypertensive peptide catestatin (CST) antagonizes
catecholamine secretion, and is a negative myocardial inotrope acting via a nitric oxide-…