User profiles for G. M. Camerino

Giulia Maria Camerino

Verified email at uniba.it
Cited by 2175

[HTML][HTML] Therapeutic approaches to genetic ion channelopathies and perspectives in drug discovery

…, GM Camerino, M De Bellis, C Camerino… - Frontiers in …, 2016 - frontiersin.org
In the human genome more than 400 genes encode ion channels, which are transmembrane
proteins mediating ion fluxes across membranes. Being expressed in all cell types, they …

[HTML][HTML] Adaptation of mouse skeletal muscle to long-term microgravity in the MDS mission

D Sandonà, JF Desaphy, GM Camerino, E Bianchini… - PloS one, 2012 - journals.plos.org
The effect of microgravity on skeletal muscles has so far been examined in rat and mice
only after short-term (5–20 day) spaceflights. The mice drawer system (MDS) program, …

[HTML][HTML] Statin-induced myopathy: translational studies from preclinical to clinical evidence

GM Camerino, N Tarantino, I Canfora… - International journal of …, 2021 - mdpi.com
Statins are the most prescribed and effective drugs to treat cardiovascular diseases (CVD).
Nevertheless, these drugs can be responsible for skeletal muscle toxicity which leads to …

[HTML][HTML] Therapeutic targets in amyotrophic lateral sclerosis: focus on ion channels and skeletal muscle

N Tarantino, I Canfora, GM Camerino, S Pierno - Cells, 2022 - mdpi.com
Amyotrophic Lateral Sclerosis is a neurodegenerative disease caused by progressive loss of
motor neurons, which severely compromises skeletal muscle function. Evidence shows that …

[HTML][HTML] Dapagliflozin protects the kidney in a non-diabetic model of cardiorenal syndrome

…, E Cianflone, S Naviglio, E Conte, GM Camerino… - Pharmacological …, 2023 - Elsevier
Cardiorenal syndrome encompasses a spectrum of disorders involving heart and kidney
dysfunction, and sharing common risk factors, such as hypertension and diabetes. Clinical …

Antioxidant treatment of hindlimb-unloaded mouse counteracts fiber type transition but not atrophy of disused muscles

…, C Digennaro, MM Dinardo, GM Camerino… - Pharmacological …, 2010 - Elsevier
… The mean chloride conductance (gCl) is calculated as the mean total membrane conductance
(gm) measured in NP solution minus the mean potassium conductance gK measured in …

Growth hormone secretagogues prevent dysregulation of skeletal muscle calcium homeostasis in a rat model of cisplatin‐induced cachexia

E Conte, GM Camerino, A Mele… - Journal of cachexia …, 2017 - Wiley Online Library
… The resting total membrane conductance (gm) was determined … The value of gm was 1/Rm
in the normal physiological solution… is an excitability parameter inversely correlated to the gm. …

Multiple pathological events in exercised dystrophic mdx mice are targeted by pentoxifylline: outcome of a large array of in vivo and ex vivo tests

…, A Liantonio, GM Camerino… - Journal of applied …, 2009 - journals.physiology.org
… C, Zallone A, Confalonieri P, Andreetta F, Arnoldi E, Courdier-Fruh I, Magyar JP, Frigeri A,
Pisoni M, Svelto M, Conte Camerino D. A multidisciplinary evaluation of the effectiveness of …

[HTML][HTML] Ryanodine channel complex stabilizer compound S48168/ARM210 as a disease modifier in dystrophin-deficient mdx mice: proof-of-concept study and …

…, M De Bellis, E Conte, S Pierno, GM Camerino… - The FASEB …, 2018 - ncbi.nlm.nih.gov
Muscle fibers lacking dystrophin undergo a long-term alteration of Ca 2+ homeostasis,
partially caused by a leaky Ca 2+ release ryanodine (RyR) channel. S48168/ARM210, an RyR …

Fluvastatin and atorvastatin affect calcium homeostasis of rat skeletal muscle fibers in vivo and in vitro by impairing the sarcoplasmic reticulum/mitochondria Ca2+ …

…, GM Camerino, S Pierno, DC Camerino - … of Pharmacology and …, 2007 - ASPET
The mechanism by which the 3-hydroxy-3-methyl-glutaryl-CoA reductase inhibitors (statins)
induce skeletal muscle injury is still under debate. By using fura-2 cytofluorimetry on intact …