… On the basis of the seminal work of Posner and co-workers in the early 1990s, the free radical
chemistry of artemisinin is now very well-defined and has been shown to involve an initial …

Publisher Summary Malaria is one of the most deadly infectious diseases known to mankind.
The species of Plasmodium that cause malaria can develop resistance to …

… The Posner group was the first to show that such oxy radicals then form carbon-centered
radicals. Carbon radicals are now internationally accepted as key initial intermediates in a …

… Gary Posner studied at the Bronx High School of Science in New York City, at Brandeis
University (BA, 1965), at Harvard … Professor Posner's research interests include developing new …

Consumption of vegetables, especially crucifers, reduces the risk of developing cancer.
Although the mechanisms of this protection are unclear, feeding of vegetables induces enzymes …

Sulforaphane [1-isothiocyanato-4-(methyl-sulfinyl)butane] was recently isolated from one
variety of broccoli as the major and very potent inducer of phase 2 detoxication enzymes in …

II. Synthetic Aspects A. 2-Pyrones 1.[4+ 2] Cycloadditions: 2-pyrones as dienes 2.[2+ 4]
Cycloadditions: 2-pyrones as dienophiles

Addition of an organometallic reagent to alpha,beta‐usaturated carbonyl compounds occurs
in one or both of two modes: attack at the carbonyl function produces a 1,2 adduct, whereas …

… sulfonate esters Into olefins has recently been presented: GH Posner, G. M. Gurrla, and K, A.
… more highly rearrangement-prone epoxides, see GH Posner and DZ Rogers, J. Am. Chem. …

Carbon‐carbon sigma‐bond formation one of the most fundamental operations in organic
chemistry, is often accomplished by interaction of an organometallic reagent with an organic …