Benzoxazole Derivatives as Novel 5-HT3 Receptor Partial Agonists in the Gut

…, M Ishikawa, T Nizato, K Suzuki, F Konno - Journal of medicinal …, 1998 - ACS Publications
… Procedure F. This procedure illustrates the general method of preparation of compounds
6r−6t. 2-Chlorobenzoxazole (10; 1.4 g, 9 mmol) was added to the solution of 1-…

[HTML][HTML] Low blood cell counts in wild Japanese monkeys after the Fukushima Daiichi nuclear disaster

…, S Nakanishi, N Ishii, T Uno, T Kato, F Konno… - Scientific reports, 2014 - nature.com
In April 2012 we carried out a 1-year hematological study on a population of wild Japanese
monkeys inhabiting the forest area of Fukushima City. This area is located 70 km from the …

[HTML][HTML] Small head size and delayed body weight growth in wild Japanese monkey fetuses after the Fukushima Daiichi nuclear disaster

…, S Nakanishi, N Ishii, T Kato, A Tanaka, F Konno… - Scientific reports, 2017 - nature.com
To evaluate the biological effect of the Fukushima Daiichi nuclear disaster, relative differences
in the growth of wild Japanese monkeys (Macaca fuscata) were measured before and …

In vivo evaluation of P-glycoprotein and breast cancer resistance protein modulation in the brain using [11C] gefitinib

…, T Yamasaki, J Yui, A Hatori, F Konno… - Nuclear medicine and …, 2009 - Elsevier
Gefitinib (Iressa) is a selective inhibitor of epidermal growth factor receptor (EGFR) tyrosine
kinase. Recent studies confirmed that gefitinib interacted with the breast cancer resistance …

[HTML][HTML] High dilutions of antimony modulate cytokines production and macrophage–Leishmania (L.) amazonensis interaction in vitro

FR de Santana, LC Dalboni, KF Nascimento, FT Konno… - Cytokine, 2017 - Elsevier
Background In previous results mice treated with high dilutions of antimony presented reduction
of monocyte migration to the site of infection with increase in B lymphocytes population …

Prenatal diagnosis of unilateral proximal femoral focal deficiency at 19 weeks' gestation: case report and review of the literature

…, A Monteagudo, K Mittal, F Konno… - … in obstetrics & …, 2011 - Wiley Online Library
Proximal femoral focal deficiency (PFFD) represents a rare and complex deformity manifested
by hypoplasia of a variable portion of the femur with shortening of the entire limb. The …

Tiludronate inhibits protein tyrosine phosphatase activity in osteoclasts

…, S Nakajo, K Nakaya, M Abe, Y Yuda, F Konno… - Bone, 1997 - Elsevier
Signaling pathways mediated by tyrosine phosphorylation and dephosphorylation have
been reported to be involved in the regulation of cytoskeletal organization in osteoclasts, the …

Chromosome elimination in the interspecific hybrid medaka between Oryzias latipes and O. hubbsi

C Sakai, F Konno, O Nakano, T Iwai, T Yokota… - Chromosome …, 2007 - Springer
An interspecific hybrid medaka (rice fish) between Oryzias latipes and O. hubbsi is embryonically
lethal. To gain an insight into the cellular and molecular mechanisms that cause the …

CytoLyt fixation significantly inhibits MIB1 immunoreactivity whereas alternative Ki‐67 clone 30‐9 is not susceptible to the inhibition: critical diagnostic implications

DJ Buonocore, F Konno, AA Jungbluth… - Cancer …, 2019 - Wiley Online Library
Background The Ki‐67 proliferation marker has multiple diagnostic and prognostic applications.
Although several clones to the Ki‐67 antigen are commercially available, the MIB1 …

Concise Synthesis of Arnottin I and (−)-Arnottin II

F Konno, T Ishikawa, M Kawahata… - The Journal of Organic …, 2006 - ACS Publications
Application of the Buchwald protocol to the coupling of o-bromobenzoates and 1-tetralones
directly affords benzodihydronaphthopyrones with a fused tetracyclic system. Aromatization …