Background and purpose. It has been shown that the reversed operation of glutamate
transporters when ATP levels fall accounts for most glutamate release induced by severe cerebral …

Estrogens account for gender differences in the incidence and outcome of stroke, but it remains
unclear to what extent neuroprotective effects of estrogens are because of parenchymal …

Growth factors promote cell growth and survival and protect the brain from developing injury
after ischemia. In this article, the authors examined whether transforming growth factor-α (…

The adult subventricular zone (SVZ) is the main neurogenic niche in the adult brain of mice
and rats. The adult SVZ contains neural stem cells (NSCs) that primarily differentiate into …

… Pérez-Asensio a , José M. Centeno b , Germán Torregrosa a b , Enrique Alborch a b …
Pérez-Asensio is recipient of a PhD fellowship from ‘Ministerio de Ciencia y Tecnologı́a’. The …

Oxidative and nitrosative stress are targets for intervention after ischemia/reperfusion. The
aim of this study was to explore the effect of CR-6, a vitamin-E analogue that is antioxidant …

As a previous step to consider their use in the pharmacology for stroke, we investigated the
effects of four phytoestrogens (ie genistein, daidzein, zearalanone and biochanin A) on …

Oxygen free radicals have been involved in the pathophysiology of cerebral ischemia,
especially after spontaneous or thrombolytic reperfusion. In this study with rats, we have …

Stroke triggers a local and systemic inflammatory response leading to the production of
cytokines that can influence blood vessel reactivity. In this study, we aimed to assess whether …

Cerebral ischemia followed by reperfusion alters vessel properties of brain arteries in rats,
inducing an inflammatory response and excessive generation of reactive oxygen species. …