Regulation of myosin heavy chain genes in the heart.

E Morkin - Circulation, 1993 - Am Heart Assoc
Advances in our knowledge of the regulation of cardiac myosin isoforms made possible by
molecular cloning of the alpha- and beta-MHCs genes are reviewed. Expression of these …

Control of cardiac myosin heavy chain gene expression

E Morkin - Microscopy research and technique, 2000 - Wiley Online Library
… Sheer D, Morkin E. 1984. Myosin isoenzyme expression in rat ventricle: effects of thyroid
hormone analogs, catecholamines, glucocorticoids and high carbohydrate diet. …

Biochemical and physiologic effects of thyroid hormone on cardiac performance

E Morkin, IL Flink, S Goldman - Progress in cardiovascular diseases, 1983 - Elsevier
Recognition of the existence of ventricular myosin isozymes and their regulation by thyroid
hormone may provide a biochemical basis for some of the effects of the hormone on …

DITPA (3, 5-diiodothyropropionic acid), a thyroid hormone analog to treat heart failure: phase II trial veterans affairs cooperative study

S Goldman, M McCarren, E Morkin, PW Ladenson… - Circulation, 2009 - Am Heart Assoc
… Dr Goldman previously owned stock in Titan; Drs Goldman, Morkin, and Ladenson were
consultants for Titan but no longer receive payments. Dr Ladenson has received grant support …

[PDF][PDF] Cardiac muscarinic cholinergic receptors. Biochemical identification and characterization.

JZ Fields, WR Roeske, E Morkin… - Journal of Biological …, 1978 - researchgate.net
The parasympathetic nervous system modulates heart rate and myocardial contractility. We
have labeled the parasympathetic muscarinic cholinergic receptors in rabbit, rat, and guinea …

Complete amino acid sequence of human thyroxine-binding globulin deduced from cloned DNA: close homology to the serine antiproteases.

…, BE Markham, E Morkin - Proceedings of the …, 1986 - National Acad Sciences
Antibodies directed against thyroxine-binding globulin (TBG) have been used to screen a
human liver lambda gt11 expression library. A 1.46-kilobase clone was identified which …

Effects of thyroid hormone on alpha-actin and myosin heavy chain gene expression in cardiac and skeletal muscles of the rat: measurement of mRNA content using …

TA Gustafson, BE Markham, E Morkin - Circulation research, 1986 - Am Heart Assoc
… Gustafson TA, Markham BE, Morkin E: Analysis of thyroid hormone effects on myosin heavy
chain gene expression in cardiac and soleus muscles using a novel dot-blot mRNA assay. …

Myocardial DNA synthesis in experimental cardiac hypertrophy

E Morkin, TP Ashford - American Journal of Physiology …, 1968 - journals.physiology.org
METHODS Myocardial DNA synthesis was investigated in ZOO-to 220-g adult female CD
rats (Charles River Breeding Laboratories, North Wilmington, Mass.) following either …

[HTML][HTML] Hormonal regulation of myosin heavy chain and alpha-actin gene expression in cultured fetal rat heart myocytes.

…, JJ Bahl, BE Markham, WR Roeske, E Morkin - Journal of Biological …, 1987 - Elsevier
Thyroid hormone regulates the expression of ventricular myosin isoenzymes by causing an
accumulation of alpha-myosin heavy chain (MHC) mRNA and inhibiting expression of beta-…

[PDF][PDF] Cardiac effects of 3, 5-diiodothyropropionic acid, a thyroid hormone analog with inotropic selectivity

…, TE Raya, JJ Bahl, S Goldman, E Morkin - … of Pharmacology and …, 1992 - prizmtx.com
Thyroid hormone exerts a strong positive inotropic action on the heart and induces a-myosin
heavy chain (MHC) gene expression. 3, 5-Diiodothyropropionic acid (DITPA), a carboxylic …