Glycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that has been implicated
in pathological conditions such as diabetes and Alzheimer's disease. We report the …

… Bromides 6c–e were synthesized as described in Scheme 2. … The anilines 30a–c were
converted to the bromides 6c–e via … with carbon may have an electronic effect with an indirect …

The pharmacological properties of a novel selective 5-hydroxytryptamine 1A (5-HT 1A )
receptor antagonist, NAD-299 [(R)-3-N,N-dicyclobutylamino-8-fluoro-3,4-dihydro-2H-1-…

We have developed two parallel series, A and B, of CX 3 CR1 antagonists for the treatment
of multiple sclerosis. By modifying the substituents on the 7-amino-5-thio-thiazolo[4,5-d]…

In this work, we consider the adaptive Wiener filtering of noisy images and image sequences.
We begin by using an adaptive weighted averaging (AWA) approach to estimate the …

OBJECTIVE: To assess health-related quality of life (HRQOL) in children and adolescents
with sickle cell disease (SCD). DESIGN, SETTING, AND PARTICIPANTS: The PedsQL 4.0 …

… The dopamine-Di (low) binding site was studied both using 'H-flupenthixol as radioligand
and by the study of the dopaminestimulated adenylate cyclase. Since 'H-flupenthixol labels …

Proximal humerus fractures in the elderly are increasing in frequency as the population ages.
The purpose of this study was to investigate surgical and cost trends in the Medicare …

Most image processing applications require noise elimination. For example, in applications
where derivative operators are applied, any noise in the image can result in serious errors. …

… In this paper we design and implement a texture segmentation system based on the work
done by Jain and Farrokhnia [5], and some recommendations given by Clausi and Jernigan [2]…