User profiles for D. Giacomini

Davide Giacomini

Ricercatore, Università degli Studi di Brescia
Verified email at unibs.it
Cited by 441

Antibacterial and antioxidant activities for natural and synthetic dual-active compounds

G Martelli, D Giacomini - European Journal of Medicinal Chemistry, 2018 - Elsevier
Antimicrobial resistance is widely recognized as a grave threat to global health in the 21st
century, since the past decades have seen a dramatic increase in human-pathogenic bacteria …

Monocyclic β-lactams: new structures for new biological activities

P Galletti, D Giacomini - Current medicinal chemistry, 2011 - ingentaconnect.com
The azetidinone core-structure offers a unique approach to the design and synthesis of new
derivatives with unique biological properties. During the last two decades researches …

Solvent effects on stereoselectivity: more than just an environment

G Cainelli, P Galletti, D Giacomini - Chemical Society Reviews, 2009 - pubs.rsc.org
Stereoselectivity is a major topic in organic synthesis. Intensive investigations into the role
of solvents on diastereo- and enantioselective reactions, as well as temperature-dependent …

[PDF][PDF] Delayed coupling to feedback inhibition during a critical period for the integration of adult-born granule cells

…, MF Trinchero, DD Alvarez, E Kropff, D Giacomini… - Neuron, 2015 - cell.com
Developing granule cells (GCs) of the adult dentate gyrus undergo a critical period of enhanced
activity and synaptic plasticity before becoming mature. The impact of developing GCs …

Involvement of bone morphogenetic protein 4 (BMP-4) in pituitary prolactinoma pathogenesis through a Smad/estrogen receptor crosstalk

…, D Giacomini, D Refojo… - Proceedings of the …, 2003 - National Acad Sciences
Pituitary tumor development involves clonal expansion stimulated by hormones and growth
factors/cytokines. Using mRNA differential display, we found that the bone morphogenetic …

A disynaptic feedback network activated by experience promotes the integration of new granule cells

DD Alvarez, D Giacomini, SM Yang, MF Trinchero… - Science, 2016 - science.org
Experience shapes the development and connectivity of adult-born granule cells (GCs) through
mechanisms that are poorly understood. We examined the remodeling of dentate gyrus …

Gene amplification of 5-enol-pyruvylshikimate-3-phosphate synthase in glyphosate-resistant Kochia scoparia

…, TA Gaines, C Preston, JP Hamilton, D Giacomini… - Planta, 2015 - Springer
Main conclusion Field-evolved resistance to the herbicide glyphosate is due to amplification
of one of two EPSPS alleles, increasing transcription and protein with no splice variants or …

Retinoic acid as a novel medical therapy for Cushing's disease in dogs

V Castillo, D Giacomini, M Páez-Pereda, J Stalla… - …, 2006 - academic.oup.com
… 0 d). The differences between the treatment groups were statistically significant at 120 d (P
< 0.05), 150 d (P < 0.01), and 180 d (P < 0.001). As shown in Fig. 1B, plasma α-MSH also …

Multiple modes of convergent adaptation in the spread of glyphosate-resistant Amaranthus tuberculatus

JM Kreiner, DA Giacomini, F Bemm… - Proceedings of the …, 2019 - National Acad Sciences
… To calculate summary statistics ( π , F ST , D xy ), we used scripts from the genomics general
pipeline available at https://github.com/simonhmartin/genomics_general, binning SNPs into …

Persistence and degradation of new β-lactam antibiotics in the soil and water environment

…, C Fellet, R Lorenzini, A Garelli, M Pori, D Giacomini - Chemosphere, 2013 - Elsevier
… Even if our data are higher (t 1/2 14.4 and 6.2 d at pH 9 and 3, respectively), this is most … t
1/2 6.2 d) was one order of magnitude lower than P1 (t 1/2 49.5 d). Nevertheless natural waters …