The extrapancreatic effects of glucagon-like peptide-1 and related peptides

…, RP Shannon, DK Andersen, D Elahi - The Journal of …, 2009 - academic.oup.com
… *Address all correspondence and requests for reprints to: Dariush Elahi, Ph.D., Departments
of Surgery and Medicine, Johns Hopkins Bayview Medical Center, 4940 Eastern Avenue, …

Diabetes and pancreatic cancer: chicken or egg?

JT Magruder, D Elahi, DK Andersen - Pancreas, 2011 - journals.lww.com
Objectives: Although half of all patients with pancreatic cancer are diabetic at the time of
diagnosis, it remains unclear whether the diabetes associated with pancreatic cancer is a cause …

The effect of age on insulin resistance and secretion: a review.

DC Muller, D Elahi, JD Tobin, R Andres - Seminars in nephrology, 1996 - europepmc.org
Aging is associated with an increased incidence of hypertension, noninsulin-dependent
diabetes mellitus, and coronary heart disease. Because these conditions often cluster in the …

Effects of glucagon-like peptide-1 in patients with acute myocardial infarction and left ventricular dysfunction after successful reperfusion

…, S Mankad, GG Sokos, G Miske, A Shah, D Elahi… - Circulation, 2004 - Am Heart Assoc
… After the baseline assessment of LV function, a 72-hour intravenous infusion of rGLP-1 (1.5
pmol/kg per minute, provided by D. Elahi, PhD, University of Massachussetts School of …

Glucagon-like peptide-1 infusion improves left ventricular ejection fraction and functional status in patients with chronic heart failure

GG Sokos, LA Nikolaidis, S Mankad, D Elahi… - Journal of cardiac …, 2006 - Elsevier
BACKGROUND: Insulin resistance is present in the setting of congestive heart failure.
Glucagon-like peptide-1 (GLP-1) is a naturally occurring incretin with both insulinotropic and …

Biomarkers of caloric restriction may predict longevity in humans

…, DK Ingram, JA Mattison, D Elahi, JD Tobin, D Muller… - Science, 2002 - science.org
These findings include CR-induced attenuation of age changes in plasma triglycerides (2)
and melatonin (3) as well as oxidative damage (4) and glucose tolerance (5). Current …

Relationship between testosterone levels, insulin sensitivity, and mitochondrial function in men

…, D Tripathy, M Yialamas, L Groop, D Elahi… - Diabetes …, 2005 - Am Diabetes Assoc
OBJECTIVE— The goal of this study was to examine the relationship between serum testosterone
levels and insulin sensitivity and mitochondrial function in men. RESEARCH DESIGN …

Recombinant glucagon-like peptide-1 increases myocardial glucose uptake and improves left ventricular performance in conscious dogs with pacing-induced dilated …

LA Nikolaidis, D Elahi, T Hentosz, A Doverspike… - Circulation, 2004 - Am Heart Assoc
… We conducted a 48-hour continuous infusion of rGLP-1 (1.5 pmol · kg −1 · min −1 , provided
by D. Elahi) administered with a MiniMed pump (model 407C, Medtronic, Inc) in 5 normal …

Increasing insulin resistance is associated with a decrease in Leydig cell testosterone secretion in men

…, E Valassi, M Yialamas, D Elahi… - The Journal of …, 2005 - academic.oup.com
… After completing blood sampling at 0800 h on d 2, … h on d 2 and 4 to suppress the HPG
axis for the remainder of the study. Pituitary sensitivity was assessed on the morning of d 3 by …

Studies in the distribution of body fat: I. Effects of age, sex, and obesity

H Shimokata, JD Tobin, DC Muller, D Elahi… - Journal of …, 1989 - academic.oup.com
The pattern of body fat distribution has been shown to be related to a large number of
variables of clinical importance. A variety of indices have been devised, many of them simple …