User profiles for D. S. Cowen

Darrel S. Cowan

Professor of Earth & Space Sciences, University of Washington
Verified email at uw.edu
Cited by 5950

Serotonin and neuronal growth factors–a convergence of signaling pathways

DS Cowen - Journal of neurochemistry, 2007 - Wiley Online Library
Monoamines, including serotonin (5‐HT), have traditionally been associated with short‐term
signaling pathways in neurons, such as the modulation of cAMP and Ca 2+ levels. In …

SptP, a Salmonella typhimurium type III‐secreted protein, inhibits the mitogen‐activated protein kinase pathway by inhibiting Raf activation

SL Lin, TX Le, DS Cowen - Cellular microbiology, 2003 - Wiley Online Library
Salmonella has developed ways to modulate host cellular response in order to survive.
Although the steps required for such modulation have been incompletely characterized, there is …

Tectonic overview of the Cordilleran orogen in the western United States

BC Burchfiel, DS Cowan, GA Davis - 1992 - pubs.geoscienceworld.org
The Cordilleran orogen, with an evolution that has spanned the entire Phanerozoic, is one
of the longest lived orogenic belts on the planet. A reason for its long history is that since at …

Structural styles in Mesozoic and Cenozoic mélanges in the western Cordillera of North America

DS Cowan - Geological Society of America Bulletin, 1985 - pubs.geoscienceworld.org
DS COWAN … (1982) concluded that the sediments they studied ranged from unconsolidated
to partly lithified at the time of deformation; Cowan (19&2) suggested that the diverse small-…

17p (p53) allelic losses, 4N (G2/tetraploid) populations, and progression to aneuploidy in Barrett's esophagus.

PC Galipeau, DS Cowan… - Proceedings of the …, 1996 - National Acad Sciences
Increased 4N (G2/tetraploid) cell populations have been postulated to be genetically
unstable intermediates in the progression to many cancers, but the mechanism by which they …

Coupling of neuronal 5‐HT7 receptors to activation of extracellular‐regulated kinase through a protein kinase A‐independent pathway that can utilize Epac

…, DR Lubinsky, DS Cowen - Journal of …, 2003 - Wiley Online Library
The roles of 3′,5′‐cyclic adenosine monophosphate (cAMP) and protein kinase A in 5‐hydroxytryptamine
(5‐HT) 7 receptor‐mediated activation of extracellular‐regulated kinase (…

Early Mesozoic tectonic evolution of the western US Cordillera

…, JS Oldow, GC Dunne, JE Wright, DS Cowan… - 1992 - pubs.geoscienceworld.org
The early Mesozoic evolution of the US Cordillera differs greatly from its previous history of
mainly miogeoclinal sedimentation with outboard marginal-basin-island-arc mobile zones. …

5-HT7 receptors activate the mitogen activated protein kinase extracellular signal related kinase in cultured rat hippocampal neurons

M Errico, RA Crozier, MR Plummer, DS Cowen - Neuroscience, 2001 - Elsevier
Medications that selectively increase 5-hydroxytryptamine are currently the most commonly
prescribed antidepressants. However, it is not known which receptors for 5-…

Do faults preserve a record of seismic slip? A field geologist's opinion

DS Cowan - Journal of Structural Geology, 1999 - Elsevier
When field geologists study natural faults, we commonly use well-established techniques to
determine the total displacement, incremental slip, and the sense of slip. What more can we …

Differential coupling of 5‐HT1 receptors to G proteins of the Gi family

…, NN Johnson‐Farley, DS Cowen - British journal of …, 2002 - Wiley Online Library
… Daniel S Cowen … Daniel S Cowen … These studies were supported by NIMH grant
MH60100 to DS Cowen. SL Lin is a Senior Research Fellow of Vion Pharmaceuticals, Inc. …