Three interleukin-1 inhibitors have been purified to homogeneity from medium conditioned by
human monocytes. Partial sequence analysis and digestion with N-glycanase indicate that …

Infection of adherent primary monocytes with HIV-1Ba-L is significantly suppressed in the
presence of human saliva. By reverse transcriptase (RT) levels, saliva, although present for …

The interleukin-1 receptor antagonist (IL-1ra) is a protein capable of inhibiting receptor
binding and biological activities of IL-1 without inducing an IL-1-like response. Equilibrium …

The natural human IL-1 receptor antagonist (IL-1ra) has been produced in a recombinant
organism and has been used to study IL-1 action in vivo. The receptor antagonist mitigates the …

Interleukin (IL-1)α and IL-1β are important mediators of inflammation. The binding of IL-1 to
interleukin-1 receptor (IL-1R) type 1 is the initial step in IL-1 signal transduction and therefore …

We have examined the binding of human and rodent interleukin-1 receptor antagonist (IL-1ra)
to the type II IL-1 receptor on the human B cell line, Raji, on the mouse pre-B cell line, 70Z/…

Secretory leukocyte protease inhibitor (SLPI) is a naturally occurring protein of human
airways that exhibits broad spectrum inhibitory activity against mast cell and leukocyte serine …

Emerging evidence suggests that mast cell tryptase is a therapeutic target for the treatment
of asthma. The effects of this serine protease are associated with both pathophysiologic …

IL-1ra: properties and uses of an interleukin-1 receptor antagonist. - Abstract - Europe PMC
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