Mutants of Saccharomyces cerevisiae were isolated which were blocked in heme biosynthesis
and required heme for growth on a nonfermentable carbon source. They were rho+, and …

Glycine, labelled with N 15, was given by mouin a. single amount of 10 mg. per kg. bodyweight
to normal human subjects on a self-selected diet and to rats by stomach tube at a level of …

Labelled ammonium citrate given to 3 rats on a high-protein diet was excreted almost
quantitatively; 2 rats on a low-protein diet utilised an appreciable fraction of the ammonia N for …

Methods Mut, ant 83-24 of Escherichia coli, which accumulates SA (1, 13), was grown in a
medium containing specifically labeled glucose as the sole carbon source. In addition, various …

Acetoacetyl CoA thiolase and 3-hydroxy-3-methylglutaryl (HMG) CoA synthase were found
almost entirely in the cytosol of Saccharomyces cerevisiae, whereas HMG CoA reductase …

The conversion of 3-enolpyruvylshikimate 5-phosphate (I) to phenylpyruvate was studied in
extracts of Escherichia coli. A separation and partial purification was achieved of the two …

Publisher Summary This chapter discusses the several aspects of the formation of shikimate,
and with its conversion to aromatic amino acids. Although the role of D-glucose is stressed …

THE study of enzyme-catalysed reactions has thrown considerable light on the geometrical
factors involved; but little is as yet known concernining the mechanism of the activation …

Tyrosine-sensitive 3-deoxy-d-arabino-heptulosonic acid 7-phosphate synthetase was
prepared by a relatively simple procedure from an operator constitutive (tyrO c ) strain of …

The enzymic synthesis of 5-enolpyruvylshikimate 3-phosphate (ES-3-P) from enolpyruvate
phosphate (labeled with 18 O in the COP oxygen) and shikimate 3-phosphate occurred with …