… yielding a 10 kDa C-terminal fragment containing all known pDyn-derived peptides (Fig. 1).
A minor alternative pathway may be the proteolytic cleavage at the Lys-Arg pair C-terminal to …

γ-aminobutyric acid (GABA) is the principal inhibitory neurotransmitter in the mammalian
brain. It acts through 2 classes of receptors, GABA A receptors that are ligand-operated on …

GABA A receptors are ligand-operated chloride channels assembled from five subunits in a
heteropentameric manner. Using immunocytochemistry, we investigated the distribution of …

… (a) focus of attention that differentiates whether attention is directed at the disease or elsewhere,
(b) sociability that describes whether the patient turns toward others or withdraws, and (c…

… fixative for 90 min at 4C, then transferred to 20% sucrose in PBS and kept there for 24 h at
4C. Thereafter the brains were rapidly frozen by immersion in −70C isopentane for 3 min and, …

… /À mice, galanin-expressing cells were almost completely absent, while the number of
sst2Aexpressing cells that contained nNOS but not galanin was substantially reduced (Figures 2C …

… pH 7.0, and the mixture was incubated at 37C for 1 hr. The reaction products were separated
by reversed-phase chromatography on a C,, column using the same elution conditions as …

Mutations in DOCK8 result in autosomal recessive Hyper-IgE syndrome with combined
immunodeficiency (CID). However, the natural course of disease, long-term prognosis, and …

… The membrane was blocked with 3% BSA, 0.5% (w/v) Triton X-100, and 0.1% (w/v)
Tween 20 dissolved in Tris-buffered saline (TBS) for either 120 min at 22C or 12–15 hr at 4C. …

… -3′), oligo-D (5′-GGAAGTCACCAACTAGAATGG-3′) and oligo-E (5′-AGCATCCAGAGAAGTGCAAC-3′),
with 35 cycles of 94C for 45 s, 60C for 1 min, and 72C for 20 s. …