User profiles for C. Mannoury la Cour
Clotilde Mannoury la CourResearch project director, Servier Verified email at essec.edu Cited by 2742 |
5‐HT6 receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia
…, S Chaumont‐Dubel, C Mannoury la Cour… - EMBO Molecular …, 2012 - embopress.org
… to mTORC1 recruitment as mTOR did not bind to the receptor C‐terminus in GST pull‐downs
using the entire receptor C‐terminal sequence as bait (Supporting Information Fig S2C). …
using the entire receptor C‐terminal sequence as bait (Supporting Information Fig S2C). …
Physical interaction between the serotonin transporter and neuronal nitric oxide synthase underlies reciprocal modulation of their activity
B Chanrion, C Mannoury la Cour… - Proceedings of the …, 2007 - National Acad Sciences
The spatiotemporal regulation of neurotransmitter transporters involves proteins that interact
with their intracellular domains. Using a proteomic approach, we identified several proteins …
with their intracellular domains. Using a proteomic approach, we identified several proteins …
Cdk5 induces constitutive activation of 5-HT6 receptors to promote neurite growth
…, S Morisset-Lopez, C Mannoury la Cour… - Nature chemical …, 2014 - nature.com
… We incubated the C-terminal domain of the mouse 5-HT 6 R (5-HT 6 Ct) fused to GST with
detergent-solubilized protein extracts from mice brain and pulled-down proteins retained by …
detergent-solubilized protein extracts from mice brain and pulled-down proteins retained by …
S32006, a novel 5-HT2C receptor antagonist displaying broad-based antidepressant and anxiolytic properties in rodent models
A Dekeyne, C Mannoury la Cour, A Gobert… - …, 2008 - Springer
… In measures of Gq-protein coupling/phospholipase C activation, S32006 displayed potent
antagonist properties at h5-HT 2C receptors (pK B values, 8.8/8.2) and h5-HT 2B receptors (…
antagonist properties at h5-HT 2C receptors (pK B values, 8.8/8.2) and h5-HT 2B receptors (…
Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing
…, JH Jhamandas, O Kann, CM la Cour… - Nature reviews Drug …, 2020 - nature.com
The brain requires a continuous supply of energy in the form of ATP, most of which is produced
from glucose by oxidative phosphorylation in mitochondria, complemented by aerobic …
from glucose by oxidative phosphorylation in mitochondria, complemented by aerobic …
Signaling at G-protein-coupled serotonin receptors: recent advances and future research directions
… Intron-rich 5-HT 4 receptors possess up to 10 C-terminal splice variants, but all share (despite
some subtle differences) similar coupling profiles, including recruitment of G s and AC. …
some subtle differences) similar coupling profiles, including recruitment of G s and AC. …
The melatonergic agonist and clinically active antidepressant, agomelatine, is a neutral antagonist at 5-HT2C receptors
…, J Bockaert, C Mannoury la Cour - International Journal …, 2011 - academic.oup.com
… Transfected HEK-293 cells were homogenized using a Polytron homogenizer (Kinematica,
Switzerland) and homogenates centrifuged at 20 000 g for 20 min at 4C. The pellet (…
Switzerland) and homogenates centrifuged at 20 000 g for 20 min at 4C. The pellet (…
[HTML][HTML] The PINK1 kinase-driven ubiquitin ligase Parkin promotes mitochondrial protein import through the presequence pathway in living cells
…, F Coge, JC Corvol, O Nosjean, C Mannoury la Cour… - Scientific reports, 2019 - nature.com
Most of over a thousand mitochondrial proteins are encoded by nuclear genes and must be
imported from the cytosol. Little is known about the cytosolic events regulating mitochondrial …
imported from the cytosol. Little is known about the cytosolic events regulating mitochondrial …
[HTML][HTML] Glutamatergic and dopaminergic modulation of cortico-striatal circuits probed by dynamic calcium imaging of networks reconstructed in microfluidic chips
…, D Guedin, Y Von Boxberg, C Mannoury la Cour… - Scientific Reports, 2018 - nature.com
… (C) Immunofluorescence images of striatal chamber receiving cortical axons at DIV 8 and
DIV 19. Notice the pre-synaptic clustering of cortical VGLUT1 on striatal arborization (MAP-2) …
DIV 19. Notice the pre-synaptic clustering of cortical VGLUT1 on striatal arborization (MAP-2) …
[HTML][HTML] P62 accumulates through neuroanatomical circuits in response to tauopathy propagation
…, CN Goulbourne, R Jeggo, C Mannoury la Cour… - Acta Neuropathologica …, 2021 - Springer
… at 4 C. Brains were incubated overnight in PBS + 30% sucrose at 4 C and frozen in OCT
compound (Fischer 4585). Brains were cut horizontally (35 µm) in a cryostat and kept at 4 C in …
compound (Fischer 4585). Brains were cut horizontally (35 µm) in a cryostat and kept at 4 C in …