Secreted Frizzled-related proteins inhibit motility and promote growth of human malignant glioma cells
W Roth, C Wild-Bode, M Platten, C Grimmel… - Oncogene, 2000 - nature.com
… and equilibrated for 30 min at 37C. The cells (3×10 4 per well) were applied to the upper
wells and allowed to migrate through the membrane at 37C in humidified air with 5% CO 2 . …
wells and allowed to migrate through the membrane at 37C in humidified air with 5% CO 2 . …
Betulinic acid-induced apoptosis in glioma cells: A sequential requirement for new protein synthesis, formation of reactive oxygen species, and caspase processing
W Wick, C Grimmel, B Wagenknecht, J Dichgans… - … of Pharmacology and …, 1999 - ASPET
Betulinic acid (BA), a pentacyclic triterpene, is an experimental cytotoxic agent for malignant
melanoma. Here, we show that BA triggers apoptosis in five human glioma cell lines. BA-…
melanoma. Here, we show that BA triggers apoptosis in five human glioma cell lines. BA-…
Predicting chemoresistance in human malignant glioma cells: the role of molecular genetic analyses
M Weller, J Rieger, C Grimmel… - … journal of cancer, 1998 - Wiley Online Library
Less than 30% of malignant gliomas respond to adjuvant chemotherapy. Here, we asked
whether alterations in the p53 and RB pathways and the expression of six BCL‐2 family …
whether alterations in the p53 and RB pathways and the expression of six BCL‐2 family …
Simultaneous targeting of multiple disease mediators by a dual-variable-domain immunoglobulin
C Wu, H Ying, C Grinnell, S Bryant, R Miller… - Nature …, 2007 - nature.com
… We chose the first five and six amino acids from the N termini of human C κ and C H1
domains, respectively, as the linker sequences for most of our constructs. Extensive Fab crystal …
domains, respectively, as the linker sequences for most of our constructs. Extensive Fab crystal …
YB-1 expression and phosphorylation regulate tumorigenicity and invasiveness in melanoma by influencing EMT
…, A Schmitt, S Forchhammer, C Grimmel… - Molecular Cancer …, 2018 - AACR
… The subcellular localization of YB-1 is governed by regulatory sequences in the C-terminal
region of the protein including two noncanonical nuclear localization signals (NLS) as well as …
region of the protein including two noncanonical nuclear localization signals (NLS) as well as …
A determination of the properties of the neutral intermediate vector boson Z0
…, P Göttlicher, C Goy, G Gratta, A Grimes, C Grinnell… - Physics Letters B, 1989 - Elsevier
We report the results of first physics runs of the L3 detector at LEP. Based on 2538 hadron
events, we determined the mass m z 0 and the width Γ z 0 of the intermediate vector boson Z 0 …
events, we determined the mass m z 0 and the width Γ z 0 of the intermediate vector boson Z 0 …
Ezrin-dependent promotion of glioma cell clonogenicity, motility, and invasion mediated by BCL-2 and transforming growth factor-β2
… and 2.5% Triton X-100, and then incubated overnight at 37C in 50 mmTris-HCl, pH 7.6, 10
m… PBS and 0.1% BSA for 30 min at 4C protected from light. The cells were washed twice with …
m… PBS and 0.1% BSA for 30 min at 4C protected from light. The cells were washed twice with …
[HTML][HTML] A narrative review of peer-led positive psychology interventions: current evidence, potential, and future directions
Positive psychology interventions are an effective means for cultivating flourishing, addressing
low levels of wellbeing, and preventing languishing. Peer-led interventions can be a …
low levels of wellbeing, and preventing languishing. Peer-led interventions can be a …
Hypericin-induced apoptosis of human malignant glioma cells is light-dependent, independent of bcl-2 expression, and does not require wild-type p53
M Weller, M Trepel, C Grimmel, M Schabet… - Neurological …, 1997 - Taylor & Francis
… their effects with those of staurosporine and calphostin C in a panel of human malignant glioma
… Calphostin C and hypericin interact with the diacylglycerol-binding regulatory domain of …
… Calphostin C and hypericin interact with the diacylglycerol-binding regulatory domain of …
[HTML][HTML] RGMa inhibition with human monoclonal antibodies promotes regeneration, plasticity and repair, and attenuates neuropathic pain after spinal cord injury
…, R Penheiro, RJ Vigouroux, L Huang, C Grinnell… - Scientific reports, 2017 - nature.com
… Neutralization of RGMa with rat antibodies recognizing the C-terminal portion of RGMa
promoted axonal growth in rats with a thoracic dorsal hemisection spinal cord lesion 13 . …
promoted axonal growth in rats with a thoracic dorsal hemisection spinal cord lesion 13 . …