Effects of serotonin in the hippocampus: how SSRIs and multimodal antidepressants might regulate pyramidal cell function

…, T Jeyarajah, Y Li, SC Leiser, G Smagin, CK Olsen… - CNS …, 2016 - cambridge.org
The hippocampus plays an important role in emotional and cognitive processing, and both
of these domains are affected in patients with major depressive disorder (MDD). Extensive …

A randomized, double-blind, placebo-controlled, duloxetine-referenced, fixed-dose study comparing the efficacy and safety of Lu AA21004 in elderly patients with …

C Katona, T Hansen, CK Olsen - International clinical …, 2012 - journals.lww.com
CK has received grant funding from Lundbeck as well as honoraria and consultancy fees
from Lundbeck, Lilly, Pfizer-Eisai and Novartis. TH and CKO are employees of Lundbeck. H. …

A randomized, double-blind, placebo-controlled study of vortioxetine on cognitive function in depressed adults

…, S Lophaven, CK Olsen - International Journal of …, 2014 - academic.oup.com
The efficacy of vortioxetine 10 and 20 mg/d vs. placebo on cognitive function and depression
in adults with recurrent moderate-to-severe major depressive disorder (MDD) was …

Tralokinumab plus topical corticosteroids for the treatment of moderate‐to‐severe atopic dermatitis: results from the double‐blind, randomized, multicentre, placebo …

…, D Hijnen, TN Jensen, B Bang, CK Olsen… - British Journal of …, 2021 - academic.oup.com
Background Tralokinumab is a fully human monoclonal antibody that specifically neutralizes
interleukin‐13, a key driver of atopic dermatitis (AD). Objectives To evaluate the efficacy …

[HTML][HTML] Efficacy and safety of vortioxetine (Lu AA21004), 15 and 20 mg/day: a randomized, double-blind, placebo-controlled, duloxetine-referenced study in the acute …

JP Boulenger, H Loft, CK Olsen - International clinical …, 2014 - journals.lww.com
This study assessed the efficacy, tolerability and safety of vortioxetine versus placebo in
adults with recurrent major depressive disorder. This double-blind, randomized, placebo-…

The effects of vortioxetine on cognitive function in patients with major depressive disorder: a meta-analysis of three randomized controlled trials

…, H Loft, W Jacobson, CK Olsen - International Journal …, 2016 - academic.oup.com
Background: Management of cognitive deficits in Major Depressive Disorder (MDD) remains
an important unmet need. This meta-analysis evaluated the effects of vortioxetine on …

Conjunctivitis in adult patients with moderate‐to‐severe atopic dermatitis: results from five tralokinumab clinical trials

…, M Boguniewicz, R Zachariae, CK Olsen… - British Journal of …, 2022 - academic.oup.com
Background Tralokinumab, a fully human IgG4 monoclonal antibody that specifically binds
with high affinity to interleukin‐13, effectively reduces moderate‐to‐severe atopic dermatitis (…

[HTML][HTML] Vortioxetine reduces BOLD signal during performance of the N-back working memory task: a randomised neuroimaging trial in remitted depressed patients …

…, R Smallman, J Buchbjerg, KG Larsen, CK Olsen… - Molecular …, 2018 - nature.com
Cognitive dysfunction is common in depression during both acute episodes and remission.
Vortioxetine is a novel multimodal antidepressant that has improved cognitive function …

IL-6 release from muscles during exercise is stimulated by lactate-dependent protease activity

…, B Lauenborg, CK Olsen… - American Journal …, 2019 - journals.physiology.org
IL-6 is secreted from muscles to the circulation during high-intensity and long-duration
exercise, where muscle-derived IL-6 works as an energy sensor to increase release of energy …

Safety of tralokinumab in adult patients with moderate‐to‐severe atopic dermatitis: pooled analysis of five randomized, double‐blind, placebo‐controlled phase II and …

…, JP Thyssen, R Zachariae, CK Olsen… - British Journal of …, 2022 - academic.oup.com
Background Tralokinumab is a fully human monoclonal antibody that neutralizes the activity
of interleukin‐13, a key pathogenic driver of atopic dermatitis (AD). Clinical trials including …