TGF-β1 expression closely associates with activation and conversion of fibroblasts to a
myofibroblast phenotype and synthesis of an alternatively spliced cellular fibronectin variant, Fn-…

The nuclear factor erythroid 2-related factor 2 (Nrf2) pathway upregulates key cellular defenses.
Clinical trials are utilizing pharmacologic Nrf2 inducers such as bardoxolone methyl to …

In this study, the effects of the light/dark cycle, hormone replacement therapy (HRT), and
nocturnal melatonin supplementation on osteogenic markers and serum melatonin levels were …

Melatonin induces cellular differentiation in numerous cell types. Data show that multiple
mechanisms are involved in these processes that are cell‐type specific and may be receptor …

The multiligand receptors megalin (Lrp2) and cubilin (Cubn) and their endocytic adaptor
protein Dab2 (Dab2) play essential roles in maintaining the integrity of the apical endocytic …

… In Swiss mice, bilateral IRI increases Nqo1 gene expression, but in CD-1 mice there was
no change [15,64]. Whereas the latter study identified other increased NRF2 targets, Nqo1 is …

… cocaine at CHO cells stably transfected with WT DAT fluctuated with cell state, yet cocaine
binding affinity was static (OT Ukairo., CD Bondi, and CK Surratt, manuscript in preparation). …

The role of NRF2 in kidney biology has received considerable interest over the past decade.
NRF2 transcriptionally controls genes responsible for cellular protection against oxidative …

Objective Melatonin and progesterone levels decline during the perimenopause. Both hormones
inhibit estrogen action and endometrial cancer, but little is known about how they act in …

Melatonin has numerous anti-cancer properties reported to influence cancer initiation,
promotion, and metastasis. With the need for effective hormone therapies (HT) to treat …