Nowadays, proteomic studies no longer focus only on identifying as many proteins as possible
in a given sample, but aiming for an accurate quantification of them. Especially in clinical …

… A positive test for hepatitis B surface antigen or human immunodeficiency virus infection
was exclusion criteria. Only patients were included without indication of a hepatocellular carci…

… DA Megger and B. Sitek acknowledge the financial support from the PROFILE-consortium
Ruhr. The project has been selected under the operational program co-financed by the …

Background Although metabolism is profoundly altered in human liver cancer, the extent to
which experimental models, eg cell lines, mimic those alterations is unresolved. Here, we …

Background & Aims Cancer cells rely on metabolic alterations to enhance proliferation and
survival. Metabolic gene alterations that repeatedly occur in liver cancer are largely unknown…

Proteomics-based clinical studies have been shown to be promising strategies for the discovery
of novel biomarkers of a particular disease. Here, we present a study of hepatocellular …

Type I interferons (IFN-I) exert pleiotropic biological effects during viral infections, balancing
virus control versus immune-mediated pathologies, and have been successfully employed …

… The typical curves are derived from an experiment where a single protein (phosphorylase
b) was … The random errors for rt are taken from the experiment with phosphorylase b. …

In order to identify new molecular markers for pancreatic intra‐epithelial neoplasias (PanINs),
the precursor lesions of pancreatic ductal adenocarcinoma, we established a proteomics …

Reactive oxygen species (ROS) are the inevitable by‐products of essential cellular metabolic
and physiological activities. Plants have developed sophisticated gene networks of ROS …