The renin–angiotensin system (RAS) mediates several classic physiologies including body
water and electrolyte homeostasis, blood pressure, cyclicity of reproductive hormones and …

The Centers for Disease Control and Prevention recommend adjunctive antitoxins when
systemic anthrax is suspected. Obiltoxaximab, a monoclonal antibody against protective …

The angiotensin (Ang) IV analog norleual [Nle-Tyr-Leu-ψ-(CH 2 -NH 2 ) 3-4 -His-Pro-Phe]
exhibits structural homology with the hinge (linker) region of hepatocyte growth factor (HGF) …

Inhalational anthrax has high mortality even with antibiotic treatment, and antitoxins are now
recommended as an adjunct to standard antimicrobial regimens. The efficacy of …

The 6-AH family [d-Nle-X-Ile-NH-(CH 2 ) 5 -CONH 2 ; where X = various amino acids] of
angiotensin IV (Ang IV) analogs binds directly to hepatocyte growth factor (HGF) and inhibit …

The angiotensin IV analog norleual [Nle-Tyr-Leu-ψ-(CH 2 -NH 2 )-Leu-His-Pro-Phe] has
been shown recently to act as a hepatocyte growth factor (HGF)/Met antagonist capable of …

l-dopa is used to treat the motor symptoms associated with Parkinson’s disease, a
neurodegenerative movement disorder characterized by a loss of dopamine neurons. l-dopa is the …

Although more than 100 years of study have demonstrated that the aldol reaction is one of
the most fundamental and effective methods for the construction of complex molecules, in …

… BRENT JOSEPH YAMAMOTO find it satisfactory and recommend that it be accepted. …
inhibits murine melanoma in vivo in male mice (Yamamoto, unpublished). Because this study was …

Rationale L-dopa, the main therapeutic for Parkinson’s disease (PD), has been shown to
increase brain dopamine concentrations that are necessary for proper motor control; however, …