[HTML][HTML] PepT1-mediated epithelial transport of dipeptides and cephalexin is enhanced by luminal leptin in the small intestine

…, F Berlioz, S Guilmeau, A Tsocas… - The Journal of …, 2001 - Am Soc Clin Investig
Dietary proteins are mostly absorbed as di- and tripeptides by the intestinal proton-dependent
transporter PepT1. We have examined the effects of leptin on PepT1 function in rat …

SAR data applications in earth observation: An overview

A Tsokas, M Rysz, PM Pardalos, K Dipple - Expert Systems with …, 2022 - Elsevier
In this review, we present the main approaches developed around satellite and airborne
Synthetic Aperture Radar (SAR) imagery. The great range of SAR imagery applications is …

Leptin stimulates the proliferation of human colon cancer cells in vitro but does not promote the growth of colon cancer xenografts in nude mice or intestinal …

T Aparicio, L Kotelevets, A Tsocas, JP Laigneau… - Gut, 2005 - gut.bmj.com
Background and aims: Leptin, the product of the ob gene, has been suggested to increase
the risk of colon cancer. However, we have shown that although leptin stimulates epithelial …

Duodenal leptin stimulates cholecystokinin secretion: evidence of a positive leptin-cholecystokinin feedback loop

S Guilmeau, M Buyse, A Tsocas, JP Laigneau… - Diabetes, 2003 - Am Diabetes Assoc
Some of the actions of leptin depend on cholecystokinin (CCK). However, it is unknown
whether leptin modulates the release of CCK. Here, we demonstrate in vitro that leptin induces …

Luminal leptin activates mucin-secreting goblet cells in the large bowel

…, R Ducroc, ME Homsi, A Tsocas… - American Journal …, 2006 - journals.physiology.org
Leptin has been suggested to be involved in tissue injury and/or mucosal defence mechanisms.
Here, we studied the effects of leptin on colonic mucus secretion and rat mucin 2 (rMuc2…

Leptin reduces the development of the initial precancerous lesions induced by azoxymethane in the rat colonic mucosa

T Aparicio, S Guilmeau, H Goiot, A Tsocas… - Gastroenterology, 2004 - Elsevier
Background & Aims : Recent studies suggest that leptin, a hormone involved in food intake
regulation, released into the circulation and gastrointestinal juice, may be a growth factor for …

PepT1-mediated fMLP transport induces intestinal inflammation in vivo

M Buyse, A Tsocas, F Walker… - American Journal of …, 2002 - journals.physiology.org
In the present study, the effect of H + /peptide transporter (PepT1)-mediatedN-formylmethionyl-leucyl-phenylalanine
(fMLP) transport on inflammation in vivo in the rat small intestine, …

Neural modulation of cephalexin intestinal absorption through the di-and tripeptide brush border transporter of rat jejunum in vivo

F Berlioz, S Julien, A Tsocas, J Chariot, C Carbon… - … of Pharmacology and …, 1999 - ASPET
Intestinal absorption of β-lactamine antibiotics (eg, cefixime and cephalexin) has been shown
to proceed through the dipeptide carrier system. In a previous study, nifedipine (NFP), an L-…

The peptide YY-preferring receptor mediating inhibition of small intestinal secretion is a peripheral Y2 receptor: pharmacological evidence and molecular cloning

…, T Voisin, AM Lorinet, R Ducroc, A Tsocas… - Molecular …, 2001 - ASPET
A peptide YY (PYY)-preferring receptor [PYY > neuropeptide Y (NPY)] was previously
characterized in rat small intestinal crypt cells, where it mediates inhibition of fluid secretion. Here, …

Several receptors mediate the antisecretory effect of peptide YY, neuropeptide Y, and pancreatic polypeptide on VIP-induced fluid secretion in the rat jejunum in vivo

A Souli, J Chariot, T Voisin, O Presset, A Tsocas… - Peptides, 1997 - Elsevier
Souli, A., J. Chariot, T. Voisin, O. Presset, A. Tsocas, A. Balasubramaniam, M. Laburthe and
C. RozÉ. Several receptors mediate the antisecretory effect of peptide YY, neuropeptide Y, …