Brain redox imaging using blood—brain barrier-permeable nitroxide MRI contrast agent
…, AG Goloshevsky, A Sulima… - Journal of Cerebral …, 2008 - journals.sagepub.com
Reactive oxygen species (ROS) and compromised antioxidant defense may contribute to
brain disorders such as stroke, amyotrophic lateral sclerosis, etc. Nitroxides are redox-sensitive …
brain disorders such as stroke, amyotrophic lateral sclerosis, etc. Nitroxides are redox-sensitive …
The abuse-related effects of pyrrolidine-containing cathinones are related to their potency and selectivity to inhibit the dopamine transporter
…, D Walther, C Jimenez-Morigosa, A Sulima… - …, 2018 - nature.com
Synthetic cathinones are common constituents of abused “bath salts” preparations and
represent a large family of structurally related compounds that function as cocaine-like inhibitors …
represent a large family of structurally related compounds that function as cocaine-like inhibitors …
High fat diet disrupts endoplasmic reticulum calcium homeostasis in the rat liver
ES Wires, KA Trychta, S Bäck, A Sulima, KC Rice… - Journal of …, 2017 - Elsevier
Background & Aims Disruption to endoplasmic reticulum (ER) calcium homeostasis has been
implicated in obesity, however, the ability to longitudinally monitor ER calcium fluctuations …
implicated in obesity, however, the ability to longitudinally monitor ER calcium fluctuations …
The structural and functional changes of blood cells and molecular components in diabetes mellitus
L Szablewski, A Sulima - Biological Chemistry, 2017 - degruyter.com
It is known fact that diabetes mellitus (DM) affects blood cells. Changes in the erythrocyte
membrane, disorder in hemoglobin oxygen-binding and modification in mechanical …
membrane, disorder in hemoglobin oxygen-binding and modification in mechanical …
Relative reinforcing effects of second-generation synthetic cathinones: Acquisition of self-administration and fixed ratio dose-response curves in rats
BM Gannon, KI Galindo, MP Mesmin, A Sulima… - …, 2018 - Elsevier
“Bath salts” preparations contain synthetic cathinones which interact with monoamine
transporters and function as either monoamine uptake inhibitors or releasers. 3,4-…
transporters and function as either monoamine uptake inhibitors or releasers. 3,4-…
Novel vaccine that blunts fentanyl effects and sequesters ultrapotent fentanyl analogues
…, EW Bow, C Whalen, OB Torres, A Sulima… - Molecular …, 2020 - ACS Publications
Active immunization is an emerging potential modality to combat fatal overdose amid the
opioid epidemic. In this study, we described the design, synthesis, formulation, and animal …
opioid epidemic. In this study, we described the design, synthesis, formulation, and animal …
Pharmacological GHSR (ghrelin receptor) blockade reduces alcohol binge-like drinking in male and female mice
RS Richardson, A Sulima, KC Rice, JA Kucharczk… - …, 2023 - Elsevier
Ghrelin is a peptide that is produced by endocrine cells that are primarily localized in the
stomach. Ghrelin receptors (GHSR) are expressed in the brain and periphery. Preclinical and …
stomach. Ghrelin receptors (GHSR) are expressed in the brain and periphery. Preclinical and …
Comparative neuropharmacology of N-(2-methoxybenzyl)-2, 5-dimethoxyphenethylamine (NBOMe) hallucinogens and their 2C counterparts in male rats
JS Elmore, AM Decker, A Sulima, KC Rice, JS Partilla… - …, 2018 - Elsevier
2,5-Dimethoxyphenethylamines (2C compounds) are 5-HT 2A/2C receptor agonists that
induce hallucinogenic effects. N-methoxybenzylation of 2C compounds markedly increases …
induce hallucinogenic effects. N-methoxybenzylation of 2C compounds markedly increases …
Bivalent conjugate vaccine induces dual immunogenic response that attenuates heroin and fentanyl effects in mice
…, C Whalen, OB Torres, A Sulima… - Bioconjugate …, 2021 - ACS Publications
Opioid use disorders and fatal overdose due to consumption of fentanyl-laced heroin remain
a major public health menace in the United States. Vaccination may serve as a promising …
a major public health menace in the United States. Vaccination may serve as a promising …
A stable heroin analogue that can serve as a vaccine hapten to induce antibodies that block the effects of heroin and its metabolites in rodents and that cross-react …
A Sulima, R Jalah, JFG Antoline… - Journal of medicinal …, 2018 - ACS Publications
An improved synthesis of a haptenic heroin surrogate 1 (6-AmHap) is reported. The
intermediate needed for the preparation of 1 was described in the route in the synthesis of 2 (…
intermediate needed for the preparation of 1 was described in the route in the synthesis of 2 (…