Peroxiredoxins: guardians against oxidative stress and modulators of peroxide signaling
A Perkins, KJ Nelson, D Parsonage, LB Poole… - Trends in biochemical …, 2015 - cell.com
Peroxiredoxins (Prxs) are a ubiquitous family of cysteine-dependent peroxidase enzymes
that play dominant roles in regulating peroxide levels within cells. These enzymes, often …
that play dominant roles in regulating peroxide levels within cells. These enzymes, often …
[HTML][HTML] Molecular mechanisms underlying the effects of statins in the central nervous system
…, GD Grant, CM McDermott, AV Perkins… - International journal of …, 2014 - mdpi.com
3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, commonly referred to as
statins, are widely used in the treatment of dyslipidaemia, in addition to providing primary and …
statins, are widely used in the treatment of dyslipidaemia, in addition to providing primary and …
Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies
…, HY Lee, KD Johnson, AS Perkins - Nucleic acids …, 2012 - academic.oup.com
Numerous examples exist of how disrupting the actions of physiological regulators of blood
cell development yields hematologic malignancies. The master regulator of hematopoietic …
cell development yields hematologic malignancies. The master regulator of hematopoietic …
[PDF][PDF] Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)
JP Liu, J Baker, AS Perkins, EJ Robertson… - cell, 1993 - cell.com
Newborn mice homozygous for a targeted disruption of insulin-like growth factor gene 1 (Igf-1)
exhibit a growth deficiency similar in severity to that prevlously observed in viable Igf-2 …
exhibit a growth deficiency similar in severity to that prevlously observed in viable Igf-2 …
Does organic farming benefit biodiversity?
The intensification and expansion of modern agriculture is amongst the greatest current
threats to worldwide biodiversity. Over the last quarter of the 20th century, dramatic declines in …
threats to worldwide biodiversity. Over the last quarter of the 20th century, dramatic declines in …
Stem cell transcriptome profiling via massive-scale mRNA sequencing
…, S Wani, G Bethel, AJ Robertson, AC Perkins… - Nature …, 2008 - nature.com
We developed a massive-scale RNA sequencing protocol, short quantitative random RNA
libraries or SQRL, to survey the complexity, dynamics and sequence content of transcriptomes …
libraries or SQRL, to survey the complexity, dynamics and sequence content of transcriptomes …
Six-item screener to identify cognitive impairment among potential subjects for clinical research
CM Callahan, FW Unverzagt, SL Hui, AJ Perkins… - Medical care, 2002 - journals.lww.com
Objective. To design a brief cognitive screener with acceptable sensitivity and specificity for
identifying subjects with cognitive impairment Design. Cohort one is assembled from a …
identifying subjects with cognitive impairment Design. Cohort one is assembled from a …
Monitoring depression treatment outcomes with the patient health questionnaire-9
Background: Although effective treatment of depressed patients requires regular follow-up
contacts and symptom monitoring, an efficient method for assessing treatment outcome is …
contacts and symptom monitoring, an efficient method for assessing treatment outcome is …
Fleet deployment optimization for liner shipping: An integer programming model
BJ Powell, AN Perkins - Maritime Policy and Management, 1997 - Taylor & Francis
Extending and improving an earlier work of the second author, an Integer Programming (IP)
model is developed to minimize the operating and lay-up costs for a fleet of liner ships …
model is developed to minimize the operating and lay-up costs for a fleet of liner ships …
An essential role in liver development for transcription factor XBP-1
XBP-1 is a CREB/ATF family transcription factor highly expressed in hepatocellular carcinomas.
Here we report that XBP-1 is essential for liver growth. Mice lacking XBP-1 displayed …
Here we report that XBP-1 is essential for liver growth. Mice lacking XBP-1 displayed …