Senescence may contribute to the pathogenesis of atherosclerosis. Although the bioavailability
of nitric oxide (NO) is limited in senescence, the effect of NO on senescence and its …

In postmenopausal women, the risk of diabetic cardiovascular disease drastically increases
compared with that of men or premenopausal women. However, the mechanism of this …

The long-term benefits of nitroglycerin therapy are limited by tolerance development.
Understanding the precise nature of mechanisms underlying nitroglycerin-induced endothelial cell …

The effect of β antagonists in the diabetic vascular lesion is controversial. We investigated
the effect of celiprolol hydrochloride, a β1 antagonist and mild β2 agonist, on the lesions and …

The present study was conducted to investigate the historical time-course changes and regional
distribution of methylmercury concentrations in preserved umbilical cords collected from …

METHODS: Under cooperation of the educational committees in 46 prefectures in Japan,
school survey was conducted for over 100,000 children of 6-8 years old and 13-15 years old …

A synthetic tripeptide alkylamide, Tyr-D-Met(0)-Gly-MPA (MPA=N-methylphenethylamide)
named “syndyphalin (SD)-33” was approximately comparable to morphine in analgesic activity …

To define the origin and evolution of recent avian infectious bronchitis virus (IBV) in Japan, a
genetic analysis was performed. By phylogenetic analysis based on the S1 gene including …

METHODS: 64 AD children (43 boys, 21 girls; mean age 2.5 years) with positive skin prick
test (SPT;> 5mm wheal) to crushed seeds of turnip rape/oilseed rape, 19 of whom had also a …