Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population

…, T Tsunoda, K Tomita, S Doi, K Fujita, A Miyatake… - Nature …, 2011 - nature.com
Bronchial asthma is a common inflammatory disease caused by the interaction of genetic
and environmental factors 1 , 2 . Through a genome-wide association study and a replication …

Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population

…, T Yamada, S Fujieda, S Tanaka, S Doi, A Miyatake… - Nature …, 2012 - nature.com
Atopic dermatitis is a common inflammatory skin disease caused by interaction of genetic
and environmental factors. On the basis of data from a genome-wide association study (GWAS…

Thymic stromal lymphopoietin gene promoter polymorphisms are associated with susceptibility to bronchial asthma

…, S Doi, M Kameda, K Fujita, A Miyatake… - American journal of …, 2011 - atsjournals.org
Thymic stromal lymphopoietin (TSLP) triggers dendritic cell–mediated T helper (Th) 2
inflammatory responses. A single-nucleotide polymorphism (SNP), rs3806933, in the promoter …

Cardiac oxidative stress in acute and chronic isoproterenol-infused rats

…, L Yao, Y Nagai, Y Fujisawa, A Miyatake… - Cardiovascular …, 2005 - academic.oup.com
Objective: Sympathetic nervous system activity in the myocardium is increased in patients
with heart failure. However, the in vivo mechanisms responsible for β-adrenoceptor-mediated …

Thylakoid luminal θ-carbonic anhydrase critical for growth and photosynthesis in the marine diatom Phaeodactylum tricornutum

…, C Nagasato, Y Tsuji, A Miyatake… - Proceedings of the …, 2016 - National Acad Sciences
The algal pyrenoid is a large plastid body, where the majority of the CO 2 -fixing enzyme,
ribulose-1,5-bisphosphate carboxylase/oxygenase (RubisCO) resides, and it is proposed to be …

Steroidogenic acute regulatory protein (StAR) transcripts constitutively expressed in the adult rat central nervous system: colocalization of StAR, cytochrome P …

A Furukawa, A Miyatake, T Ohnishi… - Journal of …, 1998 - Wiley Online Library
Steroidogenic acute regulatory protein (StAR) is a 30‐kDa protein involved in the transport
of cholesterol to the inner mitochondrial membrane and thus plays a key role in steroid …

Functional analysis of the thymic stromal lymphopoietin variants in human bronchial epithelial cells

…, S Doi, M Kameda, K Fujita, A Miyatake… - American journal of …, 2009 - atsjournals.org
Thymic stromal lymphopoietin (TSLP) is an IL-7–like cytokine that triggers dendritic cell–mediated
T helper (Th)2 inflammatory responses, and is implicated in the pathogenesis of …

Associations of functional NLRP3 polymorphisms with susceptibility to food-induced anaphylaxis and aspirin-induced asthma

…, N Shimojo, Y Kohno, K Fujita, A Miyatake… - Journal of Allergy and …, 2009 - Elsevier
BACKGROUND: NLR family, pyrin domain containing 3 (NLRP3), controls the activity of
inflammatory caspase-1 by forming inflammasomes, which leads to cleavage of the procytokines …

Aldosterone stimulates collagen gene expression and synthesis via activation of ERK1/2 in rat renal fibroblasts

…, GP Sun, M Rahman, S Kimura, A Miyatake… - …, 2005 - Am Heart Assoc
Recently, we demonstrated that in rats treated chronically with aldosterone and salt, severe
tubulointerstitial fibrosis is associated with the activation of mitogen-activated protein kinases …

Temporary angiotensin II blockade at the prediabetic stage attenuates the development of renal injury in type 2 diabetic rats

…, H Kobori, K Miyata, Y Ozawa, A Miyatake… - Journal of the …, 2005 - journals.lww.com
Whether temporary angiotensin II (AngII) blockade at the prediabetic stage attenuates renal
injury in type 2 diabetic OLETF rats later in life was investigated. OLETF rats were treated …