Characterisation of α2-adrenoceptor subtypes involved in gastric emptying, gastric motility and gastric mucosal defence
K Fülöp, Z Zádori, AZ Rónai, K Gyires - European journal of pharmacology, 2005 - Elsevier
The effect of clonidine on ethanol-induced gastric mucosal damage, gastric emptying and
gastric motility was compared. The clonidine-induced gastroprotective effect (0.03–0.09 μmol/…
gastric motility was compared. The clonidine-induced gastroprotective effect (0.03–0.09 μmol/…
Supraspinal δ-and μ-opioid receptors mediate gastric mucosal protection in the rat
K Gyires, AZ Ronai - Journal of Pharmacology and Experimental …, 2001 - ASPET
This study evaluated the contribution of supraspinal opioid receptors to gastric mucosal
protection in the rat. Intracerebroventricular (icv) and intracisternal (ic) injections of selective δ- {[d…
protection in the rat. Intracerebroventricular (icv) and intracisternal (ic) injections of selective δ- {[d…
Alpha-2 adrenergic and opioid receptor-mediated gastroprotection
K Gyires, K Müllner, S Fürst, AZ Rónai - Journal of Physiology-Paris, 2000 - Elsevier
Clonidine inhibited the development of gastric mucosal lesions induced by either acidified
ethanol or indomethacin. The ED 50 values were: 7.1 and 5.2 μg.kg –1 orally, respectively. …
ethanol or indomethacin. The ED 50 values were: 7.1 and 5.2 μg.kg –1 orally, respectively. …
Comparative study on analgesic effect of Met5-enkephalin and related lipotropin fragments
L Graf, JI Szekely, AZ Ronai, Z Dunai-Kovács, S Bajusz - Nature, 1976 - nature.com
HUGHES et al. have reported the isolation and structure of two pentapeptides from porcine
brain with opiate agonist activity in isolated systems. The structure of one of these peptides, …
brain with opiate agonist activity in isolated systems. The structure of one of these peptides, …
Structure− activity study on the Phe side chain arrangement of endomorphins using conformationally constrained analogues
…, A Borsodi, M Al-Khrasani, AZ Rónai… - Journal of medicinal …, 2004 - ACS Publications
Endomorphins-1 and -2 were substituted with all the β-MePhe stereoisomers in their Phe
residues to generate a conformationally constrained peptide set. This series of molecules was …
residues to generate a conformationally constrained peptide set. This series of molecules was …
CD and Fourier transform IR spectroscopic studies of peptides. II. Detection of β‐turns in linear peptides
Comparative CD and Fourier transform ir (FTIR) spectroscopic data on N‐Boc protected
linear peptides with or without the (Pro‐Gly) β‐turn motif (eg, Boc‐Tyr‐Pro‐Gly‐Phe‐Leu‐OH …
linear peptides with or without the (Pro‐Gly) β‐turn motif (eg, Boc‐Tyr‐Pro‐Gly‐Phe‐Leu‐OH …
Receptor constants for endomorphin-1 and endomorphin-1-ol indicate differences in efficacy and receptor occupancy
The opioid properties of endomorphin derivatives containing a C-terminal alcoholic(-ol)
function were compared to the parent amidated compounds in isolated organs (longitudinal …
function were compared to the parent amidated compounds in isolated organs (longitudinal …
[PDF][PDF] A superactive antinociceptive pentapeptide,(D-Met2, Pro5)-enkephalinamide
S Bajusz, AZ Rónai, JI Székely, L Gráf, Z Dunai-Kovács… - Febs Lett, 1977 - core.ac.uk
Our recent study [1] on synthetic analogs of enkephalins (Tyr-Gly-Gly-Phe-X, X= Met and Leu
[2]) has revealed some structural requirements for a pentapeptide to exert antinociceptive …
[2]) has revealed some structural requirements for a pentapeptide to exert antinociceptive …
Intracerebroventricular injection of clonidine releases β-endorphin to induce mucosal protection in the rat
K Gyires, AZ Rónai, K Müllner, S Fürst - Neuropharmacology, 2000 - Elsevier
The possibility that the endogenous opioid system could be involved in the central nervous
system (CNS)-mediated gastroprotective effect of clonidine was investigated. …
system (CNS)-mediated gastroprotective effect of clonidine was investigated. …
Angiotensin II-induced activation of central AT1 receptors exerts endocannabinoid-mediated gastroprotective effect in rats
K Gyires, AZ Rónai, ZS Zádori, VE Tóth… - Molecular and cellular …, 2014 - Elsevier
The aim of the present study was to analyze whether angiotensin II via the endocannabinoid
system can induce gastric mucosal protection, since transactivation of cannabinoid CB 1 …
system can induce gastric mucosal protection, since transactivation of cannabinoid CB 1 …