… Injections were made at 19:30 hours, 90 min after the onset of the dark cycle (12 hours, 6
pmto 6 am). Water intake followed food intake on a prandial basis. Results showed that nose …

… Animals were maintained under a 12 h light/dark cycle (lights on at 07:00 am). Food and
water were available ad libitum, except during the drug-testing phase of the experiment. …

The purinergic P2X 7 receptor is a ligand-gated ion channel found on peripheral macrophages
and microglia in the nervous system. Activation of P2X 7 receptors results in the rapid …

… on a 12-h light/dark cycle (lights on at 6:00 am). Animals had access to standard rat food and
water ad libitum. All animals … Experiments were carried out between 8:00 am and 4:00 pm …

10.7554/eLife.42940.001 The integrated stress response (ISR) attenuates the rate of protein
synthesis while inducing expression of stress proteins in cells. Various insults activate …

This study investigated the areas of the nucleus accumbens shell involved in the modulation
of feeding behavior by GABAergic stimulation and characterized this response using …

Primary open-angle glaucoma (POAG) is the second leading cause of irreversible blindness
worldwide. Increasing evidence suggests oxidative damage and immune response defects …

Retinal ganglion cells (RGCs) are a population of neurons of the central nervous system (CNS)
extending with their soma to the inner retina and with their axons to the optic nerve. …

Dopamine plays a role in the pathophysiology of depression and therapeutic effects of
antidepressants but the contribution of individual D 2-like receptor subtypes (D 2, D 3, D 4) to …

Background: Dysregulation of the stress‐regulatory corticotropin‐releasing factor (CRF)
system in the central nucleus of the amygdala (CeA) may be a factor in genetically determined …