… Yuanchao Zhang and Lei Lin performed the network analyses. Yuanchao Zhang and Lei
Lin contributed technical expertise to cortical thickness analysis. Tung-Ping Su, Kun-Hsien …

Gold based structures such as nanoparticles (NPs) and nanowires (NWs) have widely been
used as building blocks for sensing devices in chemistry and biochemistry fields because of …

Spaceflight is known to impose changes on human physiology with unknown molecular
etiologies. To reveal these causes, we used a multi-omics, systems biology analytical approach …

Intestinal phase I metabolism and active extrusion of absorbed drug have recently been
recognised as major determinants of oral bioavailability. Cytochrome P450 (CYP) 3A, the major …

Cytochrome P450 3A4 (CYP3A4), the major phase I drug metabolizing enzyme in humans,
and the MDR1 gene product P‐glycoprotein (P‐gp) are present at high concentrations in …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral proteins bind to host
mitochondrial proteins, likely inhibiting oxidative phosphorylation (OXPHOS) and stimulating …

Recently, many researchers have used graph theory to study the aberrant brain structures
in Alzheimer's disease (AD) and have made great progress. However, the characteristics of …

Cytochrome P-450 3A4 (CYP3A4), the major phase I drug metabolizing enzyme in humans,
and the multidrug efflux pump, MDR or P-glycoprotein (P-gp), are present at high levels in …

Pharmacokinetic drug interactions can lead to serious adverse events, and the evaluation of
a new molecular entity’s drug–drug interaction potential is an integral part of drug …

1. Pharmacokinetic drug interactions can lead to serious adverse events and the evaluation
of a new molecular entity's (NME) drug–drug interaction potential is an integral part of drug …